Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study-Reference-Cited by-同舟云学术

Clinical and Epidemiological Features of 46 Children <1 Year Old With Coronavirus Disease 2019 in Wuhan, China: A Descriptive Study

Published:2020-08-06 Issue:8 Volume:222 Page:1293-1297
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Liu Xinghua¹,Tang Jianqiao²,Xie Rong³,Li Wei¹,Chen Jianying¹,Guo Yan⁴,Zhang Bo³,Zhang Yue³,Wang Juanjuan⁵,Peng Cao⁶,Lei Xiao⁷,Luo Qunying⁷,Zhang Qiong⁷,Li Yunqiao⁷

Affiliation:

1. Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

2. Department of Pediatrics, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

3. Department of Thyroid and Breast Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

4. Wuhan Center for Disease Control and Prevention, Wuhan, China

5. Department of Rheumatology and Immunology, Anhui Provincial Children’s Hospital, Hefei, China

6. Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

7. Department of General Practice, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Abstract

Abstract The number of coronavirus disease 2019 (COVID-19) cases has exceeded 10 million. However, little is known about the epidemiology and clinical characteristics of COVID-19 infants. We collected medical information of 46 confirmed patients (<1 year old) and retrospectively analyzed epidemiological history, clinical symptoms, and laboratory test results. The median age was 5 (interquartile range, 2–7) months. Sixteen cases had fever and 27 cases had cough. Moderate disease was present in 40 cases and cardiac injury occurred in 38 cases, following by liver dysfunction in 20 cases and lymphopenia in no cases. Of all infant patients, 2 received invasive mechanical ventilation and 1 died with multiple organ dysfunction syndrome.

Funder

National Natural Science Foundation of China

Nature Science Foundation of Hubei Province

Health Research Project of Health and Family Planning Commission of Hubei Province

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

http://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiaa472/33651405/jiaa472.pdf

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