Relationship Between Hepatitis C Infection and Treatment Status and Coronavirus Disease 2019–Related Hospitalizations in Georgia

Author:

Aslanikashvili Ana1ORCID,Rylander Charlotta1ORCID,Manjavidze Tinatin12ORCID,Gamkrelidze Amiran3ORCID,Baliashvili Davit4ORCID,Anda Erik Eik1ORCID

Affiliation:

1. Department of Community Medicine, University of Tromsø—The Arctic University of Norway , Tromsø , Norway

2. Department of Medical Statistics, National Center for Disease Control and Public Health Georgia , Tbilisi , Georgia

3. School of Health Sciences, University of Georgia , Tbilisi , Georgia

4. Task Force for Global Health , Tbilisi , Georgia

Abstract

Abstract Background The aim of this study was to evaluate the impact of hepatitis C virus (HCV) infection and treatment status on coronavirus disease 2019 (COVID-19)–related hospitalizations in Georgia. Methods We analyzed 2020–2021 Georgian health registry data for COVID-19–positive individuals and categorized the data by HCV infection and treatment status. Logistic regression was used to assess the strengths of the associations. Results Treated individuals with HCV had lower odds of COVID-19–related hospitalization compared to anti-HCV-negative individuals, while untreated HCV-viremic and anti-HCV-positive nonviremic individuals had higher odds. Conclusions HCV treatment prior to COVID-19 infection was associated with lower odds of COVID-19–related hospitalization, highlighting the benefits of HCV management in the context of the pandemic.

Funder

University of Tromsø—The Arctic University of Norway

Publisher

Oxford University Press (OUP)

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