Impact of Latent Tuberculosis on Diabetes-Reference-Cited by-同舟云学术

Impact of Latent Tuberculosis on Diabetes

Published:2022-02-16 Issue:12 Volume:225 Page:2229-2234
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Tepekule Burcu¹²^ORCID,Kusejko Katharina¹²,Zeeb Marius¹²,Tarr Philip E³,Calmy Alexandra⁴,Battegay Manuel⁵,Furrer Hansjakob⁶,Cavassini Matthias⁷^ORCID,Bernasconi Enos⁸,Notter Julia⁹,Günthard Huldrych F¹,Nemeth Johannes¹,Kouyos Roger D¹²,Abela I,Aebi-Popp K,Anagnostopoulos A,Battegay M,Bernasconi E,Braun D L,Bucher H C,Calmy A,Cavassini M,Ciuffi A,Dollenmaier G,Egger M,Elzi L,Fehr J,Fellay J,Furrer H,Fux C A,Günthard H F,Hachfeld A,Haerry D,Hasse B,Hirsch H H,Hoffmann M,Hösli I,Huber M,Kahlert C R,Kaiser L,Keiser O,Klimkait T,Kouyos R D,Kovari H,Kusejko K,Martinetti G,Martinez de Tejada B,Marzolini C,Metzner K J,Müller N,Nemeth J,Nicca D,Paioni P,Pantaleo G,Perreau M,Rauch A,Schmid P,Speck R,Stöckle M,Tarr P,Trkola A,Wandeler G,Yerly S,

Affiliation:

1. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich , Zurich , Switzerland

2. Institute of Medical Virology, University of Zurich , Zurich , Switzerland

3. Department of Medicine and Division of Infectious Diseases and Hospital Epidemiology, Kantonsspital Baselland, University of Basel , Bruderholz , Switzerland

4. Division of Infectious Diseases, University Hospital Geneva, University of Geneva , Geneva , Switzerland

5. Division of Infectious Diseases and Hospital Hygiene, University Hospital Basel, University of Basel , Basel , Switzerland

6. Department of Infectious Diseases, Bern University Hospital, University of Bern , Bern , Switzerland

7. Division of Infectious Diseases, University Hospital , Lausanne , Switzerland

8. Division of Infectious Diseases, Regional Hospital Lugano , Lugano , Switzerland

9. Cantonal Hospital St Gallen, Division of Infectious Diseases and Hospital Epidemiology , St Gallen , Switzerland

Abstract

Abstract While an increased risk of active and latent tuberculosis infection (LTBI) in people with type-2 diabetes (DM) has been demonstrated, it is less well characterized whether LTBI is associated with an increased risk of developing DM. We investigated the link between LTBI and DM in people living with HIV in the Swiss HIV Cohort Study via time-dependent Cox proportional hazards models. We found that LTBI significantly increased the risk of developing DM (HR = 1.47), which was robust across different adjustment and censoring techniques. Our results thus suggest that LTBI may be associated with an increased risk of developing DM.

Funder

Swiss National Science Foundation

Swiss HIV Cohort Study

Swiss HIV Research Foundation

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiac054/42689462/jiac054.pdf

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