Mpox and Chickenpox Co-infection: Case Series from Southern Nigeria-Reference-Cited by-同舟云学术

Mpox and Chickenpox Co-infection: Case Series from Southern Nigeria

Published:2023-12-07 Issue: Volume: Page:
ISSN:0022-1899
Container-title:The Journal of Infectious Diseases
language:en
Short-container-title:

Author:

Mmerem Juliet I¹^ORCID,Umenzekwe Chukwudi C²,Johnson Mafuka S³^ORCID,Onukak Asukwo E⁴^ORCID,Chika-Igwenyi Nneka M⁵,Chukwu Kyrian S⁵,Onyeaghala Chizaram A⁶^ORCID,Ozougwu Jideofor J¹³,Alasia Datonye⁶^ORCID,Ehiakhamen Odianosen⁷^ORCID,Nwankwo Henry M²,Ezejiofor Ogochukwu I²,Unigwe Uche S¹⁵^ORCID,Iroezindu Michael O¹^ORCID

Affiliation:

1. Department of Medicine, University of Nigeria Teaching Hospital , Ituku/Ozalla, Enugu , Nigeria

2. Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital , Nnewi, Anambra State , Nigeria

3. Department of Internal Medicine, Federal University Teaching Hospital , Owerri, Imo State , Nigeria

4. Department of Internal Medicine, University of Uyo Teaching Hospital , Uyo, Akwa Ibom State , Nigeria

5. Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital , Abakaliki, Ebonyi State , Nigeria

6. Department of Internal Medicine, University of Port-Harcourt Teaching Hospital , Port-Harcourt, Rivers State , Nigeria

7. National Mpox Emergency Operating Centre, National Centre for Disease Control , Abuja , Nigeria

Abstract

Abstract Introduction We describe clinico-epidemiologic characteristics of mpox∕chickenpox co-infection in Nigeria. Methodology A retrospective cohort analysis of confirmed mpox cases in Nigeria from January 2022 to March 2023. Mpox and chickenpox were confirmed by RT-PCR. Results 56/94 (60.0%) suspected cases had confirmed mpox of whom 16 (28.6%) had chickenpox co-infection. Their median age was 29 (20-37) years, males were 24 (60.7%), 6 (10.7%) were bisexual, and 5 (8.9%) died. Mpox/chickenpox co-infected patients had more complications than mpox mono-infected cases (56.3% vs 22.5%, p = 0.015) Conclusion The high frequency of mpox/chickenpox co-infection argues for accelerated access to mpox and chickenpox vaccines in Africa.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Link

https://academic.oup.com/jid/advance-article-pdf/doi/10.1093/infdis/jiad556/54058132/jiad556.pdf

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1. Mpox Epidemiology and Risk Factors, Nigeria, 2022;Emerging Infectious Diseases;2024-09

2. Mpox outbreak in Rio de Janeiro, Brazil: A translational approach;Journal of Medical Virology;2024-04-24

3. Ending the neglect of paediatric, maternal, and congenital mpox;The Lancet Global Health;2024-04