Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection

Author:

Lidofsky Anna1,Holmes Jacinta A1,Feeney Eoin R12,Kruger Annie J1,Salloum Shadi1,Zheng Hui3,Seguin Isabel S1,Altinbas Akif1,Masia Ricard4,Corey Kathleen E1,Gustafson Jenna L1,Schaefer Esperance A1,Hunt Peter W5,Deeks Steven5,Somsouk Ma5,Chew Kara W6,Chung Raymond T1,Alatrakchi Nadia1

Affiliation:

1. Liver Center, Gastroenterology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts

2. HIV Molecular Research Group, University College of Dublin, Ireland

3. Biostatistics Center, Massachusetts General Hospital, Boston

4. Department of Pathology, Massachusetts General Hospital, Boston

5. Department of Medicine, University of California, San Francisco

6. Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Allergy and Infectious Diseases

National Institute of Mental Health

National Institute of Dental and Craniofacial Research

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Immunology and Allergy

Reference33 articles.

1. Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration;Smith;Lancet,2014

2. HCV and HIV co-infection: mechanisms and management;Chen;Nat Rev Gastroenterol Hepatol,2014

3. Mechanisms of accelerated liver fibrosis progression during HIV infection;Debes;J Clin Transl Hepatol,2016

4. Macrophages in hepatitis B and hepatitis C virus infections;Heydtmann;J Virol,2009

5. Chronic hepatitis C infection-induced liver fibrogenesis is associated with M2 macrophage activation;Bility;Sci Rep,2016

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