Everolimus with cyclosporine withdrawal or low-exposure cyclosporine in kidney transplantation from Month 3: a multicentre, randomized trial

Author:

Budde Klemens1,Zeier Martin2,Witzke Oliver3,Arns Wolfgang4,Lehner Frank5,Guba Markus6,Jacobi Johannes7,Kliem Volker8,Reinke Petra9,Hauser Ingeborg A.10,Vogt Bruno11,Stahl Rolf12,Rath Thomas13,Duerr Michael1,Paulus Eva-Maria14,May Christoph14,Porstner Martina14,Sommerer Claudia2,

Affiliation:

1. Department of Nephrology, Charité Universitätsmedizin Berlin, Berlin, Germany

2. Department of Nephrology, University of Heidelberg, Heidelberg, Germany

3. Department of Infectious Diseases and Department of Nephrology, University Duisburg-Essen, Essen, Germany

4. Department of Nephrology and Transplantation, Cologne Merheim Medical Centre, Cologne, Germany

5. Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany

6. Department of General, Visceral and Transplantation Surgery, Munich University Hospital, Campus Grosshadern, Munich, Germany

7. Department of Nephrology and Hypertension, University of Erlangen-Nuremberg, Erlangen, Germany

8. Department of Internal Medicine and Nephrology, Kidney Transplant Centre, Nephrological Centre of Lower Saxony, Klinikum Hann. Münden, Germany

9. Department of Nephrology and Intensive Care, Charité Campus Virchow, Charité-Universitätsmedizin Berlin, Berlin, Germany

10. Department of Nephrology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany

11. Department of Nephrology and Hypertension, Inselspital, Bern, Switzerland

12. III. Medical Clinic, University Hospital Hamburg, Hamburg, Germany

13. University Hospital Westpfalz, Kaiserslautern, Germany

14. Novartis Pharma GmbH, Nuernberg, Germany

Funder

Novartis Pharma GmbH, Nuernberg, Germany

Publisher

Oxford University Press (OUP)

Subject

Transplantation,Nephrology

Reference40 articles.

1. Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling;Abraham;Curr Opin Immunol,1998

2. mTOR inhibition: the learning curve in kidney transplantation;Weir;Transpl Int,2010

3. mTOR inhibitor/proliferation signal inhibitors: entering or leaving the field?;Rostaing;J Nephrol,2010

4. Reduced exposure to calcineurin inhibitors in renal transplantation;Ekberg;N Engl J Med,2007

5. Everolimus in clinical practice–renal transplantation;Pascual;Nephrol Dial Transplant,2006

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