The use of geographic information systems (GIS) in environmental science is a complex, multifaceted, and amorphous topic. Environmental science is a multidisciplinary field that integrates the biological, social, and physical sciences to address the seemingly intractable environmental problems humans face. Increasingly, GIS is the tool used to organize, analyze, manage, and visualize geospatial data that links models to derive outputs from environmental analysis and modeling. Coupled, the fields of GIS and environmental science cover a multitude of topics and approaches scattered across a broad bibliographic landscape. The environmental movement of the 1960s and 1970s fueled the development of environmental science as a disciplinary field closely related to ecology, geography, and hydrology. In the 1980s, GIS became a more accessible tool for researchers through such programs as GRASS, Intergraph, and ESRI’s ArcInfo to characterize and analyze complex environmental problems. During the 1990s, approaches to environmental science focused on risk management, pollution, and monitoring. The coincidence of Internet development, data accessibility, visualization, and software modeling tools have created a perfect storm for the adoption of an integrated approach—environmental science with an integrated technology (GIS)—to address environmental issues. There has been a virtual explosion of applications and research utilizing GIS that cover a broad range of issues: water resources, climate change, urban planning, environmental justice, vulnerability studies, etc. This bibliography provides an entrée to the complex landscape of GIS applications for environmental science. It is not an exhaustive bibliography, but one that highlights some of the main avenues of GIS applications. Utilizing the Web of Science, Academic Search Premier, and Google Scholar, key articles on GIS and environmental science were accessed and organized around various thematic areas, including Disasters, Ecology, Pollution, Public Health and Epidemiology, and Water Resources Analysis. There are numerous other areas of this topic, but selecting these areas presents the reader with an overview of the field. Many of the articles in this bibliography provide a jumping off point to explore other topic areas that are not included in this bibliography.