A Huntingtin-based peptide inhibitor of caspase-6 provides protection from mutant Huntingtin-induced motor and behavioral deficits-Reference-Cited by-同舟云学术

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A Huntingtin-based peptide inhibitor of caspase-6 provides protection from mutant Huntingtin-induced motor and behavioral deficits

Published:2015-01-23 Issue:9 Volume:24 Page:2604-2614
ISSN:1460-2083
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Aharony Israel,Ehrnhoefer Dagmar E.,Shruster Adi,Qiu Xiaofan,Franciosi Sonia,Hayden Michael R.,Offen Daniel

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/24/9/2604/14147232/ddv023.pdf

Reference34 articles.

1. Huntington's disease: from molecular pathogenesis to clinical treatment;Ross;Lancet Neurol.,2011

2. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract;Goldberg;Nat. Genet.,1996

3. Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease;Wellington;J. Neurosci.,2002

4. Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo;Graham;J. Neurosci.,2010

5. Activated caspase-6 and caspase-6-cleaved fragments of huntingtin specifically colocalize in the nucleus;Warby;Hum. Mol. Genet.,2008

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1. Magnetic Resonance Imaging to Detect Structural Brain Changes in Huntington’s Disease: A Review of Data from Mouse Models;Journal of Huntington's Disease;2024-09-10

2. Caspase inhibitors: a review on recently patented compounds (2016–2023);Expert Opinion on Therapeutic Patents;2024-08-29

3. In vivo CRISPR base editing for treatment of Huntington’s disease;2024-07-07

4. Polyglutamine disorders: Pathogenesis and potential drug interventions;Life Sciences;2024-05

5. Unraveling the Puzzle of Therapeutic Peptides: A Promising Frontier in Huntington’s Disease Treatment;Journal of Medicinal Chemistry;2024-01-11

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