CLINICAL STUDY OF ACQUIRED LARGE ABDOMINAL WALL DEFECT REPAIR WITH MULTI-LAYER MESH BRIDGING TECHNIQUE

Abstract

Abstract Aim To investigate the clinical efficacy of double-layer mesh (synthetic + biological) and “sandwich” mesh (synthetic + biological + omentum flaps) bridging techniques for the repair of large abdominal wall defect patients. Methods The clinical data of patients with large abdominal wall defect after extensive resection of abdominal neoplasms or patients with acquired large abdominal wall defect underwent multi-layer mesh bridging technique were enrolled. Patients were divided into the double-layer group (group A) and the “sandwich” group (group B). Results 23 patients underwent successful operation without perioperative mortality and serious complications. The mean abdominal wall defect area was 211.50 ± 91.01 cm2 in group A, 359.82 ± 203.96 cm2 in group B. Mean operation time was 6.92 ± 2.19 hours in group A and 5.18 ± 1.17 hours in group B. There were 6 seromas in group A and 1 in group B. Postoperatively, in group A there was 1 infection, and 3 subcutaneous effusions, whereas in group B, there was 1 hematoma, 1 subcutaneous effusion, and 1 incomplete intestinal obstruction. There was a significant difference in the short-term complication rate between the two groups. Conclusions The “sandwich” mesh bridging technique based on an omentum flap is novel and safe, and can effectively reduce postoperative complication rate. This technique can be considered as an alternative repair method for large abdominal wall defect repair and reconstruction.