1. Affiliations of authors: Department of Pediatrics (M-HC) and Graduate Institute of Clinical Medicine (C-JL, D-SC), College of Medicine, and Graduate Institute of Epidemiology (S-LY, C-JC), College of Public Health, National Taiwan University, Taipei, Taiwan; Genomics Research Center, Academia Sinica, Taipei, Taiwan (S-LY, C-JC); Division of Hepatogastroenterology, Department of Internal Medicine, Chang Gung Memorial Ho