The African Human Microbiome Portal: a public web portal of curated metagenomic metadata

Author:

Kiran Anmol,Hanachi Mariem12,Alsayed Nihad3,Fassatoui Meriem4,Oduaran Ovokeraye H5,Allali Imane6,Maslamoney Suresh7,Meintjes Ayton7,Zass Lyndon7,Rocha Jorge Da5,Kefi Rym4,Benkahla Alia1,Ghedira Kais1,Panji Sumir7,Mulder Nicola7,Fadlelmola Faisal M3ORCID,Souiai Oussema189

Affiliation:

1. Laboratory of Bioinformatics, Biomathematics and Biostatistics (LR16IPT09), Institute Pasteur of Tunis, University Tunis El Manar , Tunis 1002, Tunisia

2. Faculty of Science of Bizerte, University of Carthage , Tunis, Tunisia

3. Kush Centre for Genomics and Biomedical Informatics, Biotechnology Perspectives Organization , Khartoum, Sudan

4. Laboratory of Biomedical Genomics & Oncogenetics, Institut Pasteur de Tunis, University Tunis El Manar , Tunis 1002, Tunisia

5. The Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand , Johannesburg, South Africa

6. Laboratory of Human Pathologies Biology, Department of Biology, Faculty of Sciences, Mohammed V University in Rabat , Rabat, Morocco

7. Computational Biology Division, Department of Integrative Biomedical Sciences and Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town , Cape Town 7925, South Africa

8. Malawi-Liverpool-Wellcome Trust , Blantyre 3, Malawi

9. Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool , Liverpool CH64 7TE, UK

Abstract

Abstract There is growing evidence that comprehensive and harmonized metadata are fundamental for effective public data reusability. However, it is often challenging to extract accurate metadata from public repositories. Of particular concern is the metagenomic data related to African individuals, which often omit important information about the particular features of these populations. As part of a collaborative consortium, H3ABioNet, we created a web portal, namely the African Human Microbiome Portal (AHMP), exclusively dedicated to metadata related to African human microbiome samples. Metadata were collected from various public repositories prior to cleaning, curation and harmonization according to a pre-established guideline and using ontology terms. These metadata sets can be accessed at https://microbiome.h3abionet.org/. This web portal is open access and offers an interactive visualization of 14 889 records from 70 bioprojects associated with 72 peer reviewed research articles. It also offers the ability to download harmonized metadata according to the user’s applied filters. The AHMP thereby supports metadata search and retrieve operations, facilitating, thus, access to relevant studies linked to the African Human microbiome. Database URL:  https://microbiome.h3abionet.org/.

Funder

The National Human Genome Research Institute of the National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Information Systems

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