Annotation of gene product function from high-throughput studies using the Gene Ontology

Author:

Attrill Helen1ORCID,Gaudet Pascale2,Huntley Rachael P3,Lovering Ruth C3,Engel Stacia R4ORCID,Poux Sylvain5,Van Auken Kimberly M6,Georghiou George7ORCID,Chibucos Marcus C8ORCID,Berardini Tanya Z9,Wood Valerie10,Drabkin Harold11,Fey Petra12,Garmiri Penelope7,Harris Midori A10,Sawford Tony7,Reiser Leonore9ORCID,Tauber Rebecca8,Toro Sabrina13,

Affiliation:

1. FlyBase, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge , UK

2. CALIPHO group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, rue Michel Servet, CH Geneva, Switzerland

3. Institute of Cardiovascular Science, University College London, London, UK

4. Saccharomyces Genome Database, Department of Genetics, Stanford University, Porter Drive, Palo Alto, CA, USA

5. Swiss-Prot group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, rue Michel Servet, CH Geneva, Switzerland

6. WormBase, Division of Biology and Biological Engineering, California Institute of Technology, E California Blvd, Pasadena, CA, USA

7. European Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge, UK

8. Evidence and Conclusion Ontology, University of Maryland School of Medicine, W Baltimore St., Baltimore, MD, USA

9. The Arabidopsis Information Resource, Phoenix Bioinformatics, Redwood City, CA, USA

10. PomBase, Cambridge Systems Biology Centre and Department of Biochemistry, University of Cambridge, Sanger Building, Tennis Court Road, Cambridge, UK

11. Mouse Genome Informatics, Department of Computational Biology and Bioinformatics, The Jackson Laboratory, Main St., Bar Harbor, ME, USA

12. dictyBase, Biomedical Informatics Center and Center for Genetic Medicine, Northwestern University, Feinberg School of Medicine, North Lake Shore Drive, Chicago, IL, USA

13. Zebrafish Information Network, University of Oregon, Eugene, OR, USA

Funder

NHGRI

National Institute of General Medical Sciences

UK Wellcome Trust

National Science Foundation Division of Biological Infrastructure

European Molecular Biology Laboratory core funds

State Secretariat for Education, Research and Innovation

British Heart Foundation

Biotechnology and Biological Sciences Research Council

National Institute of Mental Health of the National Institutes of Health, National Human Genome Research Institute

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Allergy and Infectious Diseases

National Heart, Lung, and Blood Institute

National Eye Institute

National Human Genome Research Institute

National Institute for Health Research, University College London Hospitals Biomedical Research Centre

Parkinson's UK

US National Institutes of Health, National Human Genome Research Institute

UK Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Information Systems

Reference14 articles.

1. The Gene Ontology resource: 20 years and still GOing strong;The Gene Ontology Consortium;Nucleic Acids Res.,2018

2. Standardized description of scientific evidence using the Evidence Ontology (ECO);Chibucos;Database (Oxford),2014

3. Primer on the Gene Ontology;Gaudet;Methods Mol. Biol.,2017

4. The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase;Han;Curr. Biol.,2005

5. Best practices in manual annotation with the Gene Ontology;Poux;Methods Mol. Biol.,2017

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