MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle

Author:

Asplund Olof1,Rung Johan2,Groop Leif13ORCID,Prasad B Rashmi1,Hansson Ola13

Affiliation:

1. Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, Malmö 20502, Sweden

2. SciLifeLab, BMC, Husargatan 3, Uppsala University, Uppsala 751 22, Sweden

3. Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Tukholmankatu 800290 Helsinki, Finland

Abstract

Abstract MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2.

Funder

Knut och Alice Wallenbergs Stiftelse

Diabetesförbundet

Crafoordska Stiftelsen

Novo Nordisk

Swedish Foundation for Strategic Research

Linnaeus Grant

Vetenskapsrådet

Publisher

Oxford University Press (OUP)

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Information Systems

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