A BERT-based ensemble learning approach for the BioCreative VII challenges: full-text chemical identification and multi-label classification in PubMed articles

Author:

Lin Sheng-Jie1,Yeh Wen-Chao2ORCID,Chiu Yu-Wen1,Chang Yung-Chun134ORCID,Hsu Min-Huei1,Chen Yi-Shin2,Hsu Wen-Lian45

Affiliation:

1. Graduate Institute of Data Science, Taipei Medical University, No. 172-1, Section 2, Keelung Rd, Dáan District , Taipei City 106, Taiwan

2. Institute of Information Systems and Applications, National Tsing Hua University, No. 101, Section 2, Guangfu Rd, East District , Hsinchu City 300, Taiwan

3. Clinical Big Data Research Center, Taipei Medical University Hospital, No. 172-1, Section 2, Keelung Rd, Dáan District , Taipei City 106, Taiwan

4. Pervasive AI Research Labs, Ministry of Science and Technology, No. 1001, Daxue Rd, East District , Hsinchu City 300, Taiwan

5. Department of Computer Science and Information Engineering, Asia University, No. 500, Liufeng Rd, Wufeng District , Taichung City 413, Taiwan

Abstract

AbstractIn this research, we explored various state-of-the-art biomedical-specific pre-trained Bidirectional Encoder Representations from Transformers (BERT) models for the National Library of Medicine - Chemistry (NLM CHEM) and LitCovid tracks in the BioCreative VII Challenge, and propose a BERT-based ensemble learning approach to integrate the advantages of various models to improve the system’s performance. The experimental results of the NLM-CHEM track demonstrate that our method can achieve remarkable performance, with F1-scores of 85% and 91.8% in strict and approximate evaluations, respectively. Moreover, the proposed Medical Subject Headings identifier (MeSH ID) normalization algorithm is effective in entity normalization, which achieved a F1-score of about 80% in both strict and approximate evaluations. For the LitCovid track, the proposed method is also effective in detecting topics in the Coronavirus disease 2019 (COVID-19) literature, which outperformed the compared methods and achieve state-of-the-art performance in the LitCovid corpus.Database URL: https://www.ncbi.nlm.nih.gov/research/coronavirus/.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Oxford University Press (OUP)

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Information Systems

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