A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects-Reference-Cited by-同舟云学术

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

Published:2010-05-07 Issue:17 Volume:38 Page:5761-5773
ISSN:1362-4962
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Bramsen Jesper B.,Pakula Malgorzata M.,Hansen Thomas B.,Bus Claus,Langkjær Niels,Odadzic Dalibor,Smicius Romualdas,Wengel Suzy L.,Chattopadhyaya Jyoti,Engels Joachim W.,Herdewijn Piet,Wengel Jesper,Kjems Jørgen

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/38/17/5761/16766017/gkq341.pdf

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3. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes;Matranga;Cell,2005

4. Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation;Rand;Cell,2005

5. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7;Hornung;Nat. Med.,2005

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