Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

Author:

Cameron Jamie,Holla Øystein L.,Ranheim Trine,Kulseth Mari Ann,Berge Knut Erik,Leren Trond P.

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Reference29 articles.

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2. Maxwell, K.N., Soccio, R.E., Duncan, E.M., Sehayek, E. and Breslow, J.L. (2003) Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice. J. Lipid Res., 44, 2109–2119.

3. Naureckiene, S., Ma, L., Sreekumar, K., Purandare, U., Lo, C.F., Huang, Y., Chiang, L.W., Grenier, J.M., Ozenberger, B.A., Jacobsen, J.S. et al. (2003) Functional characterization of Narc 1, a novel proteinase related to proteinase K. Arch. Biochem. Biophys., 420, 55–67.

4. Dubuc, G., Chamberland, A., Wassef, H., Davignon, J., Seidah, N.G., Bernier, L. and Prat, A. (2004) Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol., 24, 1454–1459.

5. Horton, J.D., Shah, N.A., Warrington, J.A., Anderson, N.N., Park, S.W., Brown, M.S. and Goldstein, J.L. (2003) Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. Proc. Natl Acad. Sci. USA, 100, 12027–12032.

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