Evaluation of Influenza Vaccine Effectiveness Among Young Children Receiving Consecutive Versus Nonconsecutive Vaccination During Influenza A(H3N2)-Predominant Seasons

Author:

Rao Suchitra1,Moss Angela2,Lamb Molly M3,Asturias Edwin J4

Affiliation:

1. Department of Pediatrics (Infectious Diseases, Hospital Medicine and Epidemiology), University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado, USA

2. Adult and Child Center for Health Outcomes Research and Delivery Science, University of Colorado School of Medicine, Aurora, Colorado, USA

3. Department of Epidemiology and Center for Global Health, Colorado School of Public Health, Aurora, Colorado, USA

4. Department of Pediatrics, University of Colorado School of Medicine, Department of Epidemiology and Center for Global Health, Colorado School of Public Health, Aurora, Colorado, USA

Abstract

Abstract A test-negative case-control analysis of 1478 children aged 6 months to 8 years of age seeking care at an emergency/urgent care setting with influenza like illness during the 2016-17 and 2018-19 (H3N2 predominant) influenza seasons demonstrated that influenza vaccine effectiveness did not vary significantly by the prior seasons’ vaccination status. Clinical Trials Registration NCT02979626.

Funder

National Institutes of Health

National Center for Advancing Translational Sciences

Colorado Clinical and Translational Sciences Institute

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology and Child Health

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