Faster Initial Viral Decay in Female Children Living With HIV-Reference-Cited by-同舟云学术

Faster Initial Viral Decay in Female Children Living With HIV

Published:2021-01-25 Issue:5 Volume:10 Page:674-676
ISSN:2048-7207
Container-title:Journal of the Pediatric Infectious Diseases Society
language:en
Short-container-title:

Author:

Domínguez-Rodríguez Sara¹^ORCID,Serna-Pascual Miquel¹,Foster Caroline²,Palma Paolo³,Nastouli Eleni⁴,De Rossi Anita⁵,Seoane Javier⁶,Rossi Paolo³,Giaquinto Carlo⁵,Tagarro Alfredo¹^ORCID,Rojo Pablo¹

Affiliation:

1. Pediatric Infectious Diseases Unit, Fundación para la Investigación Biomédica del Hospital 12 de Octubre, Madrid, Spain

2. Imperial College Healthcare NHS Trust, London, UK

3. Division of Immune and Infectious Diseases, IRCCS Ospedale Pediatrico Bambino Gesu, Rome, Italy

4. Department of Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, London, UK

5. Department of Surgery, Oncology and Gastroenterology, Section of Oncology and Immunology, University of Padova, Padova, Italy

6. Terrestrial Ecology Group, Department of Ecology, Universidad Autónoma de Madrid, Madrid, Spain

Abstract

Abstract Limited data exist regarding sex bias and viral decay in children with HIV. We investigated the sex differences in viral decay in 25 perinatally HIV-infected children. Females presented faster phase I viral decay regardless of their age at antiretroviral therapy (ART) initiation, baseline CD4 percentages, or baseline RNA levels. Also, for each month elapsed under ART, females had faster viral decay than males.

Funder

ViiV Healthcare

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology, and Child Health

Link

http://academic.oup.com/jpids/article-pdf/10/5/674/38360596/piaa174.pdf

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