Association of HIV Exposure and HIV Infection With In-hospital Mortality Among Hospitalized Infants <1 Year of Age, South Africa, 2016

Association of HIV Exposure and HIV Infection With In-hospital Mortality Among Hospitalized Infants <1 Year of Age, South Africa, 2016–2018

Published:2023-11-11 Issue:12 Volume:12 Page:646-651
ISSN:2048-7207
Container-title:Journal of the Pediatric Infectious Diseases Society
language:en
Short-container-title:

Author:

Wolter Nicole¹²^ORCID,Walaza Sibongile¹³,von Mollendorf Claire¹,von Gottberg Anne¹²,Tempia Stefano¹,McMorrow Meredith L⁴⁵,Moyes Jocelyn¹³,Treurnicht Florette¹²,Hellferscee Orienka¹²^ORCID,Moleleki Malefu¹²,Makhasi Mvuyo¹³,Baute Neydis⁶,Cohen Cheryl¹³

Affiliation:

1. Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service , Johannesburg , South Africa

2. School of Pathology, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg , South Africa

3. School of Public Health, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg , South Africa

4. Influenza Division, Centers for Disease Control and Prevention , Atlanta, GA , USA

5. Influenza Program, Centers for Disease Control and Prevention , Pretoria , South Africa

6. Department of Paediatrics, Mapulaneng Hospital , Mpumalanga , South Africa

Abstract

Abstract We enrolled 1323 hospitalized infants aged <1 year in 2016–2018, and examined the association between HIV status and in-hospital mortality. After controlling for confounders, HIV-exposed uninfected infants did not have an increased risk of mortality, whereas infants living with HIV had 4 times greater risk compared with HIV-uninfected infants.

Funder

Centers for Disease Control and Prevention

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology and Child Health

Link

https://academic.oup.com/jpids/advance-article-pdf/doi/10.1093/jpids/piad100/53335896/piad100.pdf

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