Human Immunodeficiency Virus (HIV)-Antibody Repertoire Estimates Reservoir Size and Time of Antiretroviral Therapy Initiation in Virally Suppressed Perinatally HIV-Infected Children-Reference-Cited by-同舟云学术

Human Immunodeficiency Virus (HIV)-Antibody Repertoire Estimates Reservoir Size and Time of Antiretroviral Therapy Initiation in Virally Suppressed Perinatally HIV-Infected Children

Published:2018-08-28 Issue:5 Volume:8 Page:433-438
ISSN:2048-7193
Container-title:Journal of the Pediatric Infectious Diseases Society
language:en
Short-container-title:

Author:

Rocca Salvatore¹²,Zangari Paola²,Cotugno Nicola¹²,De Rossi Anita³,Ferns Bridget⁴,Petricone Davide¹,Rinaldi Stefano⁵,Giaquinto Carlo⁶,Bernardi Stefania⁷,Rojo Pablo⁸,Rossi Paolo¹²⁷,Pahwa Savita⁵⁹,Nastouli Eleni⁴,Palma Paolo²,Klein Nigel,Gibb Diana,Watters Sarah,Chan Man,McCoy Laura,Babiker Abdel,Marcelin Anne-Genevieve,Calvez Vincent,Munoz Maria Angeles,Wahren Britta,Foster Caroline,Cotton Mark,Robb Merlin,Ananworanich Jintanat,Claiden Polly,Pillay Deenan,Persaud Deborah,De Boer Rob J,Schröter Juliane,Anelone Anet J N,Puthanakit Thanyawee,Ceci Adriana,Giannuzzi Viviana,Luzuriaga Kathrine,Chomont Nicolas,Cameron Mark,Cancrini Caterina,Yates Andrew,Kuhn Louise,Violari Avy,Otwombe Kennedy,Pepponi Ilaria,Rocchi Francesca,Rinaldi Stefano,Tagarro Alfredo,Lain Maria Grazia,Vaz Paula,Lopez Elisa,Nhampossa Tacita,

Affiliation:

1. Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy

2. Research Unit in Congenital and Perinatal Infection, Immune and Infectious Diseases Division, Academic Department of Pediatrics (DPUO), Bambino Gesù Children’s Hospital, Rome, Italy

3. Section of Oncology and Immunology, DiSCOG, University of Padova, Italy; 3bis Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto (IOV)-IRCCS, Padova, Italy

4. Virology Laboratory, Clinical Microbiology and Virology, University College London Hospital NHS Foundation Trust, London, United Kingdom

5. Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Florida

6. Department of Women’s and Children’s Health, University of Padova, Italy

7. Academic Department of Pediatrics (DPUO), Bambino Gesù Children’s Hospital-University of Rome Tor Vergata, Italy

8. Department of Pediatrics, Pediatric Infectious Diseases Unit, Hospital 12 de Octubre, Universidad Complutense, Madrid, Spain

9. Miami Center for AIDS Research, Miller School of Medicine, University of Miami, Florida

Abstract

Different specific antibody responses against 10 HIV-1 viral proteins detected by Western blot, plasma assay on a very small amount of plasma (20 μL) can estimate HIV-DNA size and timing of ART initiation in long-term virally suppressed children.

Funder

PENTA-ID Foundation

ViiV Healthcare UK

National Institutes of Health

Children’s Hospital Bambino Gesú

Associazione Volontari Bambino Gesù

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology and Child Health

Link

http://academic.oup.com/jpids/article-pdf/8/5/433/30437013/piy080.pdf