Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician’s Dilemma-Reference-Cited by-同舟云学术

Clostridioides difficile Infection in Pediatric Inflammatory Bowel Disease: A Clinician’s Dilemma

Published:2021-08-03 Issue:Supplement_3 Volume:10 Page:S41-S45
ISSN:2048-7207
Container-title:Journal of the Pediatric Infectious Diseases Society
language:en
Short-container-title:

Author:

Conrad Máire A¹²^ORCID,Kelsen Judith R¹²

Affiliation:

1. Division of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

2. Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA

Abstract

Abstract Clostridioides difficile infection (CDI) in children with inflammatory bowel disease (IBD) can present and manifest differently from the general population with CDI, and it can worsen the underlying disease course. Furthermore, current clinical assays used to test for CDI do not accurately distinguish between true CDI or colonization. This uncertainty leads to difficulty in identifying the etiology and therapy for symptomatic patients with IBD. Improved diagnostic tests, biomarkers, and safe and effective treatment options are greatly needed for this vulnerable population.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology, and Child Health

Link

https://academic.oup.com/jpids/article-pdf/10/Supplement_3/S41/41165021/piab069.pdf

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