Diagnostic Yield of Saliva for SARS-CoV-2 Molecular Testing in Children

Author:

Banerjee Dithi12,Sasidharan Anjana1,Abdulhamid Ayah1,Orosco Esmeralda M1,Watts Jennifer L23,Schuster Jennifer E23,Myers Angela L23,Weddle Gina3,Selvarangan Rangaraj12ORCID

Affiliation:

1. Department of Pathology and Laboratory Medicine, Children’s Mercy, Kansas City, Missouri, USA

2. University of Missouri - Kansas City School of Medicine, Kansas City, Missouri, USA

3. Department of Pediatrics, Children’s Mercy, Kansas City, Missouri, USA

Abstract

Abstract Pediatric saliva specimen demonstrated high sensitivity (93%) and specificity (96.2%) compared to paired nasopharyngeal swabs (NPS) by Aptima SARS-CoV-2 Assay (Aptima). Viral loads were comparable in both specimen types. Saliva is a safe, noninvasive, and acceptable alternative specimen for SARS-CoV-2 detection in children.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology, and Child Health

Reference12 articles.

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