Features Associated With Radiographic Pneumonia in Children with SARS-CoV-2

Author:

Florin Todd A1ORCID,Freedman Stephen B2ORCID,Xie Jianling3,Funk Anna L3ORCID,Tancredi Daniel J4,Kim Kelly3,Neuman Mark I5,Yock-Corrales Adriana6,Bergmann Kelly R7,Breslin Kristen A8,Finkelstein Yaron9,Ahmad Fahd A10ORCID,Avva Usha R11,Lunoe Maren M12,Chaudhari Pradip P13,Shah Nipam P14,Plint Amy C15,Sabhaney Vikram J16,Sethuraman Usha17,Gardiner Michael A18,Sartori Laura F19,Wright Bruce20,Navanandan Nidhya21,Mintegi Santiago22,Gangoiti Iker22,Borland Meredith L23,Chong Shu-Ling24ORCID,Kwok Maria Y25,Eckerle Michelle26,Poonai Naveen27,Romero Carlos Miguel Angelats28,Waseem Muhammad29,Nebhrajani Jasmine R30,Bhatt Maala31,Caperell Kerry32,Campos Carmen33,Becker Sarah M34,Morris Claudia R35,Rogers Alexander J36,Kam April J37,Pavlicich Viviana38,Palumbo Laura39,Dalziel Stuart R4041,Morrison Andrea K42,Rino Pedro B43,Cherry Jonathan C44,Salvadori Marina I45,Ambroggio Lilliam21,Klassen Terry P46,Payne Daniel C47ORCID,Malley Richard48,Simon Norma-Jean49,Kuppermann Nathan50

Affiliation:

1. Division of Emergency Medicine, Department of Pediatrics, Ann and Robert H. Lurie Children’s Hospital of Chicago, Feinberg School of Medicine, Northwestern University , Chicago , USA

2. Sections of Pediatric Emergency Medicine and Gastroenterology, Departments of Pediatrics and Emergency Medicine, Cumming School of Medicine, University of Calgary , Calgary , Canada

3. Department of Pediatrics, Cumming School of Medicine, University of Calgary , Calgary , Canada

4. Department of Pediatrics, University of California , Davis , USA

5. Division of Emergency Medicine, Department of Pediatrics, Harvard Medical School, Boston Children’s Hospital , Boston, Massachusetts , USA

6. Department of Emergency Medicine, Hospital Nacional de Niños “Dr. Carlos Sáenz Herrera”, CCSS , San José , Costa Rica

7. Department of Emergency Medicine, Children’s Minnesota , Minneapolis , USA

8. Division of Emergency Medicine, Children’s National Hospital , Washington, District of Columbia , USA

9. Divisions of Emergency Medicine, and Clinical Pharmacology and Toxicology, Department of Pediatrics Hospital for Sick Children , Toronto , Canada

10. Department of Pediatrics, Washington University School of Medicine , St. Louis , USA

11. Department of Emergency Medicine, Montefiore-Nyack Hospital , Nyack, New York , USA

12. Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh , Pittsburgh , USA

13. Division of Emergency and Transport Medicine, Children’s Hospital Los Angeles and Keck School of Medicine of the University of Southern California , Los Angeles , USA

14. Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Alabama at Birmingham , Birmingham , USA

15. Division of Emergency Medicine, Children’s Hospital of Eastern Ontario, Department of Pediatrics, University of Ottawa , Ottawa , Canada

16. Department of Paediatrics, University of British Columbia , Vancouver , Canada

17. Division of Emergency Medicine, Department of Pediatrics, Children’s Hospital of Michigan, Central Michigan University , Detroit , USA

18. Department of Pediatrics, Rady Children’s Hospital, University of California San Diego , San Diego , USA

19. Division of Pediatric Emergency Medicine, Department of Pediatrics, Children’s Hospital of Philadelphia , Philadelphia , USA

20. Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Alberta, Stollery Children’s Hospital, Women’s and Children’s Health Research Institute , Edmonton , Canada

21. Section of Emergency Medicine, Department of Pediatrics, Children’s Hospital Colorado, University of Colorado , Aurora , USA

22. Pediatric Emergency Department, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, UPV/EHU , Bilbao, Basque Country , Spain

23. Divisions of Emergency Medicine and Paediatrics, School of Medicine, Perth Children’s Hospital, University of Western Australia , Perth , Australia

24. Department of Emergency Medicine, KK Women’s and Children’s Hospital, Pediatrics Academic Clinical Programme, Emergency Medicine Academic Clinical Programme, Duke-NUS Medical School , Singapore

25. Department of Emergency Medicine, New York Presbyterian Morgan Stanley Children’s Hospital, Columbia University Irving Medical Center , NY, New York , USA

26. Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children’s Hospital , Cincinnati , USA

27. Department of Pediatrics, Schulich School of Medicine & Dentistry , London , Canada

28. Department of Pediatrics, Hospital Francesc de Borja , Gandia , Spain

29. Department of Pediatrics, Lincoln Medical Center , New York City, Bronx, New York , USA

30. Department of Pediatrics, St. Mary’s Medical Center , West Palm Beach , USA

31. Department of Pediatrics, Children’s Hospital of Eastern Ontario, University of Ottawa , Ottawa , Canada

32. Division of Emergency Medicine, Department of Pediatrics, University of Louisville, Norton Children’s Hospital , Louisville , USA

33. Pediatric Emergency Department, Hospital Universitario Miguel Servet , Zaragoza , Spain

34. Department of Pediatrics, Primary Children’s Hospital, Intermountain Healthcare , Salt Lake City , USA

35. Division of Emergency Medicine, Department of Pediatrics, Emory University School of Medicine, Children’s Healthcare of Atlanta , Atlanta , USA

36. Departments of Emergency Medicine and Pediatrics, University of Michigan School of Medicine , Ann Arbor , USA

37. Division of Emergency Medicine, Department of Pediatrics, McMaster Children’s Hospital , Hamilton , Canada

38. Departamento de Emergencia Pediátrica, Facultad de Medicina, Hospital General Pediátrico Niños de Acosta Ñu, Universidad Privada del Pacífico , San Lorenzo , Paraguay

39. Department of Pediatrics, ASST Spedali Civili di Brescia - Pronto soccorso pediatrico , Brescia , Italy

40. Children’s Emergency Department, Starship Children’s Hospital , Auckland , New Zealand

41. Departments of Surgery and Paediatrics: Child and Youth Health, University of Auckland , Auckland , New Zealand

42. Division of Emergency Medicine, Department of Pediatrics, Medical College of Wisconsin , Milwaukee , USA

43. Department of Pediatrics, Hospital de Pediatría “Prof. Dr. Juan P. Garrahan”, RIDEPLA , Buenos Aires , Argentina

44. Department of Pediatric Emergency Medicine, IWK Health Centre, Dalhousie University , Halifax , Canada

45. Public Health Agency of Canada , Ottawa , Canada

46. Department of Pediatrics and Child Health, Children’s Hospital Research Institute of Manitoba, University of Manitoba , Winnipeg , Canada

47. Centers for Disease Control and Prevention , Atlanta, Georgia , USA

48. Division of Infectious Diseases, Boston Children’s Hospital and Harvard Medical School , Boston , USA

49. Data Analytics and Reporting and Division of Emergency Medicine, Ann and Robert H Lurie Children’s Hospital of Chicago , Chicago, Illinois , USA

50. Departments of Emergency Medicine and Pediatrics, University of California, Davis School of Medicine , Sacramento , USA

Abstract

14% of children with SARS-CoV-2 infections had radiographic pneumonia. Hypoxemia, cough, higher temperature, and older age were associated with pneumonias. In children tested, SARS-CoV-2 test results were not associated with radiographic pneumonia.

Publisher

Oxford University Press (OUP)

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