A Possible Case of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Newborn With Positive Placental In Situ Hybridization of SARS-CoV-2 RNA

Author:

Alamar Ihab1,Abu-Arja Mohammad H1,Heyman Taryn2,Roberts Drucilla J3,Desai Niyati4,Narula Pramod1,Dygulska Beata1

Affiliation:

1. Department of Pediatrics, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, USA

2. Department of Obstetrics and Gynecology, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, USA

3. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

4. Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA

Abstract

Abstract Little is known about the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the coronavirus disease 2019 (COVID-19) on pregnant mothers and their infants. Moreover, there is no definitive evidence that SARS CoV- 2 can be vertically transmitted from an infected mother to the unborn fetus.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology and Child Health

Reference4 articles.

1. Detection of SARS-CoV-2 in placentas with pathology and vertical transmission;Zhang;Am J Obstet Gynecol MFM,2020

2. SARS-CoV-2 can infect the placenta and is not associated with specific placental histopathology: a series of 19 placentas from COVID-19-positive mothers;Hecht;Mod Pathol,2020

3. Placental pathology in COVID-19;Shanes;Am J Clin Pathol,2020

4. Pathology of congenital Zika syndrome in Brazil: a case series;Martines;Lancet,2016

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