Rotavirus Vaccine Impact Within an Integrated Healthcare Delivery System in the United States

Author:

Burke Rachel M1ORCID,Tate Jacqueline E1,Groom Holly2,Parashar Umesh D1,Mattison Claire P13,Donald Judy2,Salas S Bianca2,Naleway Allison L2,Lee Mi H2,Dickerson John F2,Biggs Christianne4,Tsaknaridis Laura4,Bowen Michael D1,Schmidt Mark2,Hall Aron J1

Affiliation:

1. Division of Viral Diseases, Centers for Disease Control and Prevention , Atlanta, Georgia , USA

2. Center for Health Research, Kaiser Permanente Northwest , Portland, Oregon , USA

3. Cherokee Nation Assurance , Arlington, Virginia , USA

4. Oregon State Public Health Laboratory , Portland, Oregon , USA

Abstract

Abstract We assessed rotavirus vaccine impact using data on acute gastroenteritis (AGE) encounters within an integrated healthcare delivery system during 2000–2018. Following rotavirus vaccine introduction, all-cause AGE rates among children <5 years declined by 36% (95% confidence interval [CI]: 32%–40%) for outpatient and 54% (95% CI: 46%–60%) for inpatient encounters.

Funder

Kaiser Permanente Center for Health Research

CDC Foundation

Takeda Vaccines, Inc

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology and Child Health

Reference11 articles.

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