Hypermethylation in H3K9me3 regions characterizes the centenarian methylomes in healthy aging

Author:

Xiao Fu-Hui12,Wang Hao-Tian123ORCID,Chen Xiao-Qiong1,Ge Ming-Xia123,Yan Dongjing4,Yang Xing-Li1,Yang Li-Qin12,Lin Rong5ORCID,Guo Rong-Hui123,Zhang Wen4,Tang Nelson Leung-Sang26,He Yonghan1ORCID,Zhou Jumin7,Cai Wang-Wei4,Kong Qing-Peng182

Affiliation:

1. State Key Laboratory of Genetic Resources and Evolution, Key Laboratory of Healthy Aging Research of Yunnan Province, Kunming Key Laboratory of Healthy Aging Study, Kunming Institute of Zoology, Chinese Academy of Sciences , China

2. KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases , China

3. Kunming College of Life Science, University of Chinese Academy of Sciences , China

4. Department of Biochemistry and Molecular Biology, Hainan Medical College , China

5. Department of Biology, Hainan Medical College , China

6. Department of Chemical Pathology and Laboratory for Genetics of Disease Susceptibility, Li Ka Shing Institute of Health Sciences, and School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong , China

7. Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Key Laboratory of Healthy Aging Research of Yunnan Province, Kunming Institute of Zoology , China

8. CAS Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences , China

Funder

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Multidisciplinary

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