Homocysteine Synthesis Is Elevated but Total Remethylation Is Unchanged by the Methylenetetrahydrofolate Reductase 677C→T Polymorphism and by Dietary Folate Restriction in Young Women

Author:

Davis Steven R.,Quinlivan Eoin P.,Shelnutt Karla P.,Ghandour Haifa,Capdevila Antonieta,Coats Bonnie S.,Wagner Conrad,Shane Barry,Selhub Jacob,Bailey Lynn B.,Shuster Jonathan J.,Stacpoole Peter W.,Gregory Jesse F.

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference40 articles.

1. Homocysteine and risk of ischemic heart disease. A meta analysis;The Homocysteine Studies Collaboration;J. Am. Med. Assoc.,2002

2. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population;Selhub;J. Am. Med. Assoc.,1993

3. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase;Frosst;Nat. Genet.,1995

4. The effect of 677CT and 1298AC mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects;Chango;Br. J. Nutr.,2000

5. Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase;Yamada;Nat. Struct. Biol.,2001

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