Repeating themes of plastic genes and therapeutic schemes targeting the ‘tandem repeatome’
Author:
Affiliation:
1. Florey Institute of Neuroscience and Mental Health, University of Melbourne , Parkville , Australia
2. Department of Anatomy and Physiology, University of Melbourne , Parkville , Australia
Abstract
Funder
National Health and Medical Research
European Union Joint Progamme—Neurodegenerative Disease Research
ERA-NET NEURON
Flicker of Hope Foundation
DHB Foundation
Margaret Friend Trust and Hunter’s Huntington’s Disease Research Gift
Publisher
Oxford University Press (OUP)
Link
https://academic.oup.com/braincomms/advance-article-pdf/doi/10.1093/braincomms/fcae047/56708377/fcae047.pdf
Reference15 articles.
1. Tandem repeats mediating genetic plasticity in health and disease;Hannan;Nat Rev Genet,2018
2. Identification of genetic factors that modify clinical onset of Huntington’s disease;Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium;Cell,2015
3. Modification of Huntington’s disease by short tandem repeats;Hong;Brain Commun,2024
4. Tandem repeat polymorphisms: Modulators of disease susceptibility and candidates for ‘missing heritability’;Hannan;Trends Genet,2010
5. Genome-wide detection of tandem DNA repeats that are expanded in autism;Trost;Nature,2020
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