Imported Case of Lassa Fever in Sweden With Encephalopathy and Sensorineural Hearing Deficit

Author:

Grahn Anna1,Bråve Andreas2,Lagging Martin3,Dotevall Leif4,Ekqvist David5,Hammarström Helena33,Karlberg Helen2,Lagerqvist Nina2,Sansone Martina6,Tegnell Anders7,Ulleryd Peter14,Studahl Marie1

Affiliation:

1. Departments of Infectious Medicine

2. Microbiology and

3. Clinical Microbiology, and

4. Department of Communicable Disease Control and Prevention, Västra Götaland Region, Sweden; Departments of

5. Division of Infectious Diseases, Department of Clinical and Experimental Medicine, Linköping University, Sweden

6. Clinical Microbiology/Healthcare Hygiene, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Sweden

7. Monitoring and Evaluation, Public Health Agency of Sweden, Solna

Abstract

Abstract We describe an imported case of Lassa fever with both encephalopathy and bilateral sensorineural hearing deficit. Absence of fever during hospitalization, initially nonspecific symptoms, and onset of hearing deficit in a late stage of disease probably contributed to delayed diagnosis (14 days after admittance to hospital). The pathogenesis of neurological manifestations of Lassa fever is poorly understood and no specific treatment was given. A total of 118 personnel had close contact with the patient, but no secondary cases occurred. This case highlights the importance of considering Lassa fever as a differential diagnosis in patients with recent travel to endemic areas.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference16 articles.

1. A case-control study of the clinical diagnosis and course of Lassa fever;McCormick;J Infect Dis,1987

2. A prospective study of the epidemiology and ecology of Lassa fever;McCormick;J Infect Dis,1987

3. Lassa fever;World Health Organization (WHO)

4. Clinical features of Lassa fever in Liberia;Frame;Rev Infect Dis,1989

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