Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents

Author:

Lottrup Grete1,Belling Kirstine2,Leffers Henrik1,Nielsen John E.1,Dalgaard Marlene D.134,Juul Anders1,Skakkebæk Niels E.1,Brunak Søren23,Rajpert-De Meyts Ewa1

Affiliation:

1. Department of Growth and Reproduction, Copenhagen University Hospital(Rigshospitalet), International Center for Research and Training in Endocrine Disruption of Male Reproduction & Child Health (EDMaRC), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark

2. Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark

3. Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark (DTU), DK-2800 Lyngby, Denmark

4. DTU Multi-Assay Core (DMAC), Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, DK-2800 Lyngby, Denmark

Funder

Danish Cancer Society

Capital Region's Research Fund for Health Research

Rigshospitalet's research funds

Villum Kann Rasmussen Foundation

Danish Innovation Fund

ReproUnion

Kirsten and Freddy Johansen's foundation

Novo Nordisk Foundation

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,Obstetrics and Gynecology,Genetics,Molecular Biology,Embryology,Reproductive Medicine

Reference62 articles.

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2. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias;Bolstad;Bioinformatics,2003

3. Endocrine regulation and communicating functions of the Leydig Cell;Dufau;Annu Rev Physiol,1988

4. Genetic variation, expression and ontogeny of sulfotransferase SULT2A1 in humans;Ekström;Pharmacogenomics J,2015

5. The Reactome pathway Knowledgebase;Fabregat;Nucleic Acids Res,2016

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