The Onset and Progression of Chronic Colitis Parallels Increased Mucosal Serotonin Release via Enterochromaffin Cell Hyperplasia and Downregulation of the Serotonin Reuptake Transporter

Author:

Stavely Rhian12,Fraser Sarah3,Sharma Shilpa2,Rahman Ahmed A14,Stojanovska Vanesa15,Sakkal Samy1,Apostolopoulos Vasso3,Bertrand Paul6,Nurgali Kulmira12

Affiliation:

1. College of Health and Biomedicine, Victoria University; Western Centre for Health, Research and Education, Sunshine Hospital, Melbourne, Victoria, Australia

2. Department of Medicine, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Regenerative Medicine and Stem Cells Program, Australian Institute of Musculoskeletal Science (AIMSS), Western Health

3. Centre for Chronic Disease; College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia

4. Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia

5. Hudson Institute of Medical Research; Monash Health Translation Precinct, Melbourne, Victoria, Australia

6. School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Melbourne, Victoria, Australia

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Reference69 articles.

1. The fundamental basis of inflammatory bowel disease;Strober;J Clin Invest,2007

2. Treatment of inflammatory bowel disease (IBD);Pithadia;Pharmacol Rep,2011

3. Efficacy and complications of surgery for Crohn’s disease;Lewis;Gastroenterol Hepatol (N Y),2010

4. Serotonin and GI disorders: an update on clinical and experimental studies;Manocha;Clin Transl Gastroenterol,2012

5. Serotonin is a sword and a shield of the bowel: serotonin plays offense and defense;Gershon;Trans Am Clin Climatol Assoc,2012

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