The Impact of Combination Therapy on Infliximab Levels and Antibodies in Children and Young Adults With Inflammatory Bowel Disease

Author:

Chi Lisa Yue12,Zitomersky Naamah Levy12,Liu Enju13,Tollefson Sophia12,Bender-Stern Julia12,Naik Snehal4,Snapper Scott125,Bousvaros Athos12

Affiliation:

1. Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Boston Children’s Hospital, Boston, Massachusetts

2. Harvard Medical School, Boston, Massachusetts

3. Institutional Centers for Clinical and Translational Research, Boston Children’s Hospital, Boston, Massachusetts

4. Prometheus Laboratories Inc., San Diego, California 92121

5. Division of Gastroenterology, Brigham and Women’s Hospital, Boston, Massachusetts, USA

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Reference26 articles.

1. A 10-year, single tertiary care center experience on the durability of infliximab in pediatric inflammatory bowel disease;Vahabnezhad;Inflamm Bowel Dis,2014

2. Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial;Hanauer;Lancet,2002

3. Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn’s disease in children: REACH open-label extension;Hyams;Curr Med Res Opin,2011

4. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn’s disease;Baert;N Engl J Med,2003

5. Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn’s disease;Hanauer;Clin Gastroenterol Hepatol,2004

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