Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7
Author:
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/45/13/7870/22894753/gkx483.pdf
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4. Aggregation of polyglutamine-expanded ataxin 7 protein specifically sequesters ubiquitin-specific protease 22 and deteriorates its deubiquitinating function in the Spt-Ada-Gcn5-acetyltransferase (SAGA) complex;J. Biol. Chem.,2015
5. Poly(Q) expansions in ATXN7 affect solubility but not activity of the SAGA deubiquitinating module;Mol. Cell. Biol.,2015
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