LUNG CANCER LIFETIME RISKS IN COHORT STUDIES OF URANIUM MINERS

Author:

Tomasek Ladislav1

Affiliation:

1. Dept of Research & Development, National Radiation Protection Institute, Prague CZ14000, Czech Republic

Abstract

Abstract The article summarizes the most recent results from the cohorts of uranium miners, particularly the risks at low exposures and the risk models with modifying effects of exposure rate, age and time since exposure, which are used for the calculation of lifetime risks (LRs). The excess relative risks per unit exposure (ERR/WLM) arising from low exposures were found up to 10 times higher than the crude risk coefficients. For studies that reported models with modifying effect of age, time since exposure and exposure rate, LRs were calculated using the BEIR VI projection. These LRs were also calculated for a model with effect modification on the annual exposure rate. The results were prepared for the UNSCEAR report on ‘Lung cancer from exposure to radon.’(1)

Funder

European Commission

Czech Ministry of the Interior

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health,Radiology Nuclear Medicine and imaging,General Medicine,Radiation,Radiological and Ultrasound Technology

Reference19 articles.

1. The alpha-risk project;Alpha-Risk Consortium;Eur. Parliament Mag.,2008

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