1. Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia , Via Alessandro Brambilla, 74, 27100 Pavia PV , Italy
2. Intensive Care, Fondazione Policlinico San Matteo Hospital IRCCS , Viale Camillo Golgi, 19, 27100 Pavia PV , Italy
3. Levine Cardiac Intensive Care Unit, Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School , 60 Fenwood Road, Suite 7022, Boston, MA 02115 , USA