1. Pauley Heart Center, Virginia Commonwealth University , 1200 E. Broad Street, Richmond, VA 23298 , USA
2. Robert M. Berne Cardiovascular Research Center, and Division of Cardiology, University of Virginia , 415 Lane Road,Charlottesville, VA 22908 , USA
3. Department of Medicine and Surgery, University of Insubria , Viale Borri 57, Varese 21100 , Italy
4. Department of Pharmacotherapy & Outcomes Sciences, Virginia Commonwealth University , 410 N. 12th Street, Richmond, VA 23298 , USA