Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Consensus Document of the Acute CardioVascular Care (ACVC) association and the ESC council of Cardio-Oncology—Part 1: acute coronary syndromes and acute pericardial diseases

Author:

Gevaert Sofie A1ORCID,Halvorsen Sigrun2,Sinnaeve Peter R3,Sambola Antonia4,Gulati Geeta2,Lancellotti Patrizio5ORCID,Van Der Meer Peter6,Lyon Alexander R7,Farmakis Dimitrios8,Lee Geraldine9,Boriani Giuseppe10ORCID,Wechalekar Ashutosh11,Okines Alicia12,Asteggiano Riccardo1314ORCID

Affiliation:

1. Department of Cardiology, Ghent University Hospital, C Heymanslaan 10, 9000 Gent, Belgium

2. Department of Cardiology, Oslo University Hospital Ulleval and University of Oslo, Kirkeveien 166, 0450 Oslo, Norway

3. Department of Cardiology, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium

4. Department of Cardiology, University Hospital Vall d’Hebron, Universitat Autonòma, CIBER-CV, Passeig de la Vall d'Hebron 119, 08035 Barcelona, Spain

5. University of Liège Hospital, GIGA Cardiovascular Science and Department of Cardiology, CHU Sart Tilman, Avenue del'Hôpital 1, 4000 Liège, Belgium

6. Department of Cardiology, University of Groningen University Medical Center Groningen and University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands

7. Cardio-Oncology Clinic at Royal Brompton Hospital and Imperial College, Sydney street, SW3 6NP London, UK

8. University of Cyprus Medical School, Agio Nikolaou street 93, 2408 Nicosia, Cyprus

9. Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King’s College, Strand, WC2R 2LS London, UK

10. Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia and Policlinico Di Modena, Via Giuseppe Campi 287, 41125 Modena, Italy

11. Department of Haematology, University College London/University College London Hospitals, Huntley street 72, WC1E 6DD London, UK

12. Department of Medicine, The Royal Marsden NHS Foundation Trust, Fulham road 203, SW3 6JJ London, UK

13. Insubria University, Via Ravasi 2, 21100 Varese, Italy

14. LARC (Laboratorio Analisi e Ricerca Clinica), Via Mombarcaro 80, 10136 Turin, Italy

Abstract

Abstract Advances in treatment, common cardiovascular (CV) risk factors and the ageing of the population have led to an increasing number of cancer patients presenting with acute CV diseases. These events may be related to the cancer itself or the cancer treatment. Acute cardiac care specialists must be aware of these acute CV complications and be able to manage them. This may require an individualized and multidisciplinary approach. We summarize the most common acute CV complications of cytotoxic, targeted, and immune-based therapies. This is followed by a proposal for a multidisciplinary approach where acute cardiologists work close together with the treating oncologists, haematologists, and radiation specialists, especially in situations where immediate therapeutic decisions are needed. In this first part, we further focus on the management of acute coronary syndromes and acute pericardial diseases in patients with cancer.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Critical Care and Intensive Care Medicine,General Medicine

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