Care of patients with ST-elevation myocardial infarction: an international analysis of quality indicators in the acute coronary syndrome STEMI Registry of the EURObservational Research Programme and ACVC and EAPCI Associations of the European Society of Cardiology in 11 462 patients-Reference-Cited by-同舟云学术

Care of patients with ST-elevation myocardial infarction: an international analysis of quality indicators in the acute coronary syndrome STEMI Registry of the EURObservational Research Programme and ACVC and EAPCI Associations of the European Society of Cardiology in 11 462 patients

Published:2022-11-08 Issue:1 Volume:12 Page:22-37
ISSN:2048-8726
Container-title:European Heart Journal. Acute Cardiovascular Care
language:en
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Author:

Ludman Peter¹^ORCID,Zeymer Uwe²^ORCID,Danchin Nicolas³^ORCID,Kala Petr⁴^ORCID,Laroche Cécile⁵,Sadeghi Masoumeh⁶^ORCID,Caporale Roberto⁷^ORCID,Shaheen Sameh Mohamed⁸^ORCID,Legutko Jacek⁹^ORCID,Iakobishvili Zaza¹⁰^ORCID,Alhabib Khalid F¹¹^ORCID,Motovska Zuzana¹²^ORCID,Studencan Martin¹³^ORCID,Mimoso Jorge¹⁴^ORCID,Becker David¹⁵^ORCID,Alexopoulos Dimitrios¹⁶^ORCID,Kereseselidze Zviad¹⁷^ORCID,Stojkovic Sinisa¹⁸¹⁹^ORCID,Zelveian Parounak²⁰^ORCID,Goda Artan²¹^ORCID,Mirrakhimov Erkin²²²³^ORCID,Bajraktari Gani²⁴^ORCID,Farhan Hasan Ali²⁵^ORCID,Šerpytis Pranas²⁶,Raungaard Bent²⁷,Marandi Toomas²⁸²⁹^ORCID,Moore Alice May³⁰^ORCID,Quinn Martin³¹^ORCID,Karjalainen Pasi Paavo³²^ORCID,Tatu-Chitoiu Gabriel³³^ORCID,Gale Chris P⁵³⁴^ORCID,Maggioni Aldo P⁵³⁵^ORCID,Weidinger Franz³⁶^ORCID,Goda A,Shuka N,Pavli E,Tafaj E,Gishto T,Dibra A,Duka A,Gjana A,Kristo A,Knuti G,Demiraj A,Dado E,Hasimi E,Simoni L,Siqeca M,Sisakian H,Hayrapetyan H,Markosyan S,Galustyan L,Arustamyan N,Kzhdryan H,Pepoyan S,Zirkik A,Von Lewinski D,Paetzold S,Kienzl I,Matyas K,Neunteufl T,Nikfardjam M,Neuhold U,Mihalcz A,Glaser F,Steinwender C,Reiter C,Grund M,Hrncic D,Hoppe U,Hammerer M,Hinterbuchner L,Hengstenberg C,Karth G Delle,Lang I,Weidinger F,Winkler W,Hasun M,Kastner J,Havel C,Derntl M,Oberegger G,Hajos J,Adlbrecht C,Publig T,Leitgeb M-C,Wilfing R,Jirak P,Ho C-Y,Puskas L,Schrutka L,Spinar J,Parenica J,Hlinomaz O,Fendrychova V,Semenka J,Sikora J,Sitar J,Groch L,Rezek M,Novak M,Kramarikova P,Stasek J,Dusek J,Zdrahal P,Polasek R,Karasek J,Seiner J,Sukova N,Varvarovsky I,Lazarák T,Novotny V,Matejka J,Rokyta R,Volovar S,Belohlavek J,Motovska Z,Siranec M,Kamenik M,Kralik R,Raungaard B,Ravkilde J,Jensen S E,Villadsen A,Villefrance K,Skov C Schmidt,Maeng M,Moeller K,Hasan-Ali H,Ahmed T A,Hassan M,ElGuindy A,Ismail M Farouk,Ibrahim Abd El-Aal A,Gaafar A El-sayed,Hassan H Magdy,Ahmed Shafie M,Nabil El-khouly M,Bendary A,Darwish M,Ahmed Y,Amin O A,AbdElHakim A,Abosaif K,Kandil H,Galal M A G,El Hefny E E,El-Sayed M,Aly K,Mokarrab M,Osman M,Abdelhamid M,Mantawy S,Ali M R,Kaky S D,Khalil V A,Saraya M E A,Talaat A,Nabil M,Mounir W M,Aransa K Mahmoud A,Kazamel G,Anwar S,Al-Habbaa A,Abd el Monem M,Ismael A,Amin Abu-Sheaishaa M,Abd Rabou M M,Hammouda T M A,Moaaz M,Elkhashab K,Ragab T,Rashwan A,Rmdan A,AbdelRazek G,Ebeid H,Ghareeb H Soliman,Farag N,Zaki M,Seleem M,Torki A,Youssef M,AlLah Nasser N A,Rafaat A,Selim H,Makram M M,Khayyal M,Malasi K,Madkour A,Kolib M,Alkady H,Nagah H,Yossef M,Wafa A,Mahfouz E,Faheem G,Moris M Magdy,Ragab A,Ghazal M,Mabrouk A,Hassan M,El-Masry M,Naseem M,Samir S,Marandi T,Reinmets J,Allvee M,Saar A,Ainla T,Vaide A,Kisseljova M,Pakosta U,Eha J,Lotamois K,Sia J,Myllymaki J,Pinola T,Karjalainen P P,Paana T,Mikkelsson J,Ampio M,Tsivilasvili J,Zurab P,Kereselidze Z,Agladze R,Melia A,Gogoberidze D,Khubua N,Totladze L,Metreveli I,Chikovani A,Eitel I,Pöss J,Werner M,Constantz A,Ahrens C,Zeymer U,Tolksdorf H,Klinger S,Sack S,Heer T,Lekakis J,Kanakakis I,Xenogiannis I,Ermidou K,Makris N,Ntalianis A,Katsaros F,Revi E,Kafkala K,Mihelakis E,Diakakis G,Grammatikopoulos K,Voutsinos D,Alexopoulos D,Xanthopoulou I,Mplani V,Foussas S,Papakonstantinou N,Patsourakos N,Dimopoulos A,Derventzis A,Athanasiou K,Vassilikos V P,Papadopoulos C,Tzikas S,Vogiatzis I,Datsios A,Galitsianos I,Koutsampasopoulos K,Grigoriadis S,Douras A,Baka N,Spathis S,Kyrlidis T,Hatzinikolaou H,Kiss R G,Becker D,Nowotta F,Tóth K,Szabó S,Lakatos C,Jambrik Z,Ruzsa J,Ruzsa Z,Róna S,Toth J,Kosik A Vargane,Toth K S B,Nagy G G,Ondrejkó Z,Körömi Z,Botos B,Pourmoghadas M,Salehi A,Massoumi G,Sadeghi M,Soleimani A,Sarrafzadegan N,Roohafza H,Azarm M,Mirmohammadsadeghi A,Rajabi D,Rahmani Y,Siabani S,Najafi F,Hamzeh B,Karim H,Siabani H,Saleh N,Charehjoo H,Zamzam L,Al-Temimi G,Al-Farhan H,Al-Yassin A,Mohammad A,Ridha A,Al-Saedi G,Atabi N,Sabbar O,Mahmood S,Dakhil Z,Yaseen I F,Almyahi M,Alkenzawi H,Alkinani T,Alyacopy A,Kearney P,Twomey K,Iakobishvili Z,Shlomo N,Beigel R,Caldarola P,Rutigliano D,Saponetti L Sublimi,Locuratolo N,Palumbo V,Scherillo M,Formigli D,Canova P,Musumeci G,Roncali F,Metra M,Lombardi C,Visco E,Rossi L,Meloni L,Montisci R,Pippia V,Marchetti M F,Congia M,Cacace C,Luca G,Boscarelli G,Indolfi C,Ambrosio G,Mongiardo A,Spaccarotella C,De Rosa S,Canino G,Critelli C,Caporale R,Chiappetta D,Battista F,Gabrielli D,Marziali A,Bernabò P,Navazio A,Guerri E,Manca F,Gobbi M,Oreto G,Andò G,Carerj S,Saporito F,Cimmino M,Rigo F,Zuin G,Tuccillo B,Scotto di Uccio F,Irace L,Lorenzoni G,Meloni I,Merella P,Polizzi G M,Pino R,Marzilli M,Morrone D,Caravelli P,Orsini E,Mosa S,Piovaccari G,Santarelli A,Cavazza C,Romeo F,Fedele F,Mancone M,Straito M,Salvi N,Scarparo P,Severino P,Razzini C,Massaro G,Cinque A,Gaudio C,Barillà F,Torromeo C,Porco L,Mei M,Iorio R,Nassiacos D,Barco B,Sinagra G,Falco L,Priolo L,Perkan A,Strana M,Bajraktari G,Percuku L,Berisha G,Mziu B,Beishenkulov M,Abdurashidova T,Toktosunova A,Kaliev K,Serpytis P,Serpytis R,Butkute E,Lizaitis M,Broslavskyte M,Xuereb R G,Moore A M,Balbi M Mercieca,Paris E,Buttigieg L,Musial W,Dobrzycki S,Dubicki A,Kazimierczyk E,Tycinska A,Wojakowski W,Kalanska-Lukasik B,Ochala A,Wanha W,Dworowy S,Sielski J,Janion M,Janion-Sadowska A,Dudek D,Wojtasik-Bakalarz J,Bryniarski L,Peruga J Z,Jonczyk M,Jankowski L,Klecha A,Legutko J,Michalowska J,Brzezinski M,Kozmik T,Kowalczyk T,Adamczuk J,Maliszewski M,Kuziemka P,Plaza P,Jaros A,Pawelec A,Sledz J,Bartus S,Zmuda W,Bogusz M,Wisnicki M,Szastak G,Adamczyk M,Suska M,Czunko P,Opolski G,Kochman J,Tomaniak M,Miernik S,Paczwa K,Witkowski A,Opolski M P,Staruch A D,Kalarus Z,Honisz G,Mencel G,Swierad M,Podolecki T,Marques J,Azevedo P,Pereira M A,Gaspar A,Monteiro S,Goncalves F,Leite L,Mimoso J,Manuel Lopes dos Santos W,Amado J,Pereira D,Silva B,Caires G,Neto M,Rodrigues R,Correia A,Freitas D,Lourenco A,Ferreira F,Sousa F,Portugues J,Calvo L,Almeida F,Alves M,Silva A,Caria R,Seixo F,Militaru C,Ionica E,Tatu-Chitoiu G,Istratoaie O,Russian M Florescu,Lipnitckaia E,Osipova O,Konstantinov S,Bukatov V,Vinokur T,Egorova E,Nefedova E,Levashov S,Gorbunova A,Redkina M,Karaulovskaya N,Bijieva F,Babich N,Smirnova O,Filyanin R,Eseva S,Kutluev A,Chlopenova A,Shtanko A,Kuppar E,Shaekhmurzina E,Ibragimova M,Mullahmetova M,Chepisova M,Kuzminykh M,Betkaraeva M,Namitokov A,Khasanov N,Baleeva L,Galeeva Z,Magamedkerimova F,Ivantsov E,Tavlueva E,Kochergina A,Sedykh D,Kosmachova E,Skibitskiy V,Porodenko N,Namitokov A,Litovka K,Ulbasheva E,Niculina S,Petrova M,Harkov E,Tsybulskaya N,Lobanova A,Chernova A,Kuskaeva A,Kuskaev A,Ruda M,Zateyshchikov D,Gilarov M,Konstantinova E,Koroleva O,Averkova A,Zhukova N,Kalimullin D,Borovkova N,Tokareva A,Buyanova M,Khaisheva L,Pirozhenko A,Novikova T,Yakovlev A,Tyurina T,Lapshin K,Moroshkina N,Kiseleva M,Fedorova S,Krylova L,Duplyakov D,Semenova Y,Rusina A,Ryabov V,Syrkina A,Demianov S,Reitblat O,Artemchuk A,Efremova E,Makeeva E,Menzorov M,Shutov A,Klimova N,Shevchenko I,Elistratova O,Kostyuckova O,Islamov R,Budyak V,Ponomareva E,Jan U Ullah,Alshehri A M,Sedky 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Affiliation:

1. Institute of Cardiovascular Sciences, University of Birmingham , Birmingham , UK

2. Klinikum der Stadt Ludwigshafen and Institut für Herzinfarktforschung , Ludwigshafen am Rhein , Germany

3. Hôpital Européen Georges Pompidou, Service de Cardiologie Paris , Paris , France

4. Department of Internal Medicine and Cardiology, Medical Faculty of Masaryk University, University Hospital Brno , Brno , Czech Republic

5. EURObservational Research Programme, European Society of Cardiology , Sophia Antipolis , France

6. Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences , Isfahan , Iran

7. Interventional Cardiology Unit, Annunziata Civil Hospital , Cosenza , Italy

8. Ain Shams University , Cairo , Egypt

9. Department of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, John Paul II Hospital , Krakow , Poland

10. Rabin Medical Center , Petah Tikva , Israel

11. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University , Riyadh , Saudi Arabia

12. Cardiocenter, Third Faculty of Medicine Charles University and University Hospital Kralovske Vinohrady , Prague , Czech Republic

13. Cardiocentre Presov, Teaching Hospital of J.A. Reiman , Presov , Slovakia

14. Centro Hospitalar e Universitário do Algarve , Faro , Portugal

15. Heart and Vascular Center, Semmelweis University , Budapest , Hungary

16. National and Kapodistrian University of Athens, Attikon University Hospital , Athens , Greece

17. Chapidze Emergency Cardiology Center , Tbilisi , Georgia

18. Faculty of Medicine, University of Belgrade , Belgrade , Serbia

19. Department of Cardiology, Clinical Center of Serbia , Belgrade , Serbia

20. Scientific Research Institute of Cardiology named after Levon Hovhannisyan , Yerevan , Armenia

21. Cardiology I and Cardiology II, University Hospital Center Mother Theresa , Tirana , Albania

22. Kyrgyz State Medical Academy , Bishkek , Kyrgyzstan

23. National Center of Cardiology and Internal Medicine , Bishkek , Kyrgyzstan

24. Medical Faculty, University of Prishtina ‘Hasan Prishtina’, University Clinical Centre of Kosova , Prishtina, Kosovo

25. Iraqi Board for Medical Specializations, Scientific Council of Cardiology, Baghdad Heart Centre , Medical City, Baghdad , Iraq

26. Vilnius University Faculty of Medicine , Vilnius , Lithuania

27. Department of Cardiology, Aalborg University Hospital , Aalborg , Denmark

28. Centre of Cardiology, North Estonia Medical Centre , Tallinn , Estonia

29. Department of Cardiology, University of Tartu , Tartu , Estonia

30. Mater Dei Hospital , Msida , Malta

31. St Vincent’s University Hospital , Dublin 4 , Ireland

32. Heart and Lung Center, Helsinki University Hospital and Helsinki University , Helsinki , Finland

33. Spitalul Clinic de Urgenta ‘Floreasca’ , Bucharest , Romania

34. Department of Cardiology, Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds Teaching Hospitals NHS Trust , Leeds , UK

35. ANMCO Research Center, Heart Care Foundation , Florence , Italy

36. Hospital Rudolfstiftung , Vienna , Austria

Abstract

Abstract Aims To use quality indicators to study the management of ST-segment elevation myocardial infarction (STEMI) in different regions. Methods and results Prospective cohort study of STEMI within 24 h of symptom onset (11 462 patients, 196 centres, 26 European Society of Cardiology members, and 3 affiliated countries). The median delay between arrival at a percutaneous cardiovascular intervention (PCI) centre and primary PCI was 40 min (interquartile range 20–74) with 65.8% receiving PCI within guideline recommendation of 60 min. A third of patients (33.2%) required transfer from their initial hospital to one that could perform emergency PCI for whom only 27.2% were treated within the quality indicator recommendation of 120 min. Radial access was used in 56.6% of all primary PCI, but with large geographic variation, from 76.4 to 9.1%. Statins were prescribed at discharge to 98.7% of patients, with little geographic variation. Of patients with a history of heart failure or a documented left ventricular ejection fraction ≤40%, 84.0% were discharged on an angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and 88.7% were discharged on beta-blockers. Conclusion Care for STEMI shows wide geographic variation in the receipt of timely primary PCI, and is in contrast with the more uniform delivery of guideline-recommended pharmacotherapies at time of hospital discharge.

Funder

Abbott Vascular Int

Amgen Cardiovascular

AstraZeneca

Bayer AG

Boehringer Ingelheim

Boston Scientific

The Bristol Myers Squibb

Pfizer Alliance

Daiichi Sankyo Europe GmbH

The Alliance Daiichi Sankyo Europe GmbH

Eli Lilly and Company