Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity
Author:
Affiliation:
1. Synthetic Biology, Institut Pasteur, Université Paris Cité , CNRS UMR 6047, 75015 Paris , France
2. Collège Doctoral, Sorbonne Université , F-75005 Paris , France
Abstract
Funder
European Research Council
Agence Nationale de la Recherche
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
https://academic.oup.com/nar/article-pdf/51/7/3485/49875857/gkad170.pdf
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4. RNA-guided editing of bacterial genomes using CRISPR–Cas systems;Jiang;Nat. Biotechnol.,2013
5. Defining synonymous codon compression schemes by genome recoding;Wang;Nature,2016
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