Interaction between baseline and early worsening of renal function and efficacy of renin-angiotensin-aldosterone system blockade in patients with heart failure: insights from the Val-HeFT study

Author:

Lesogor Anastasia1,Cohn Jay N.2,Latini Roberto3,Tognoni Gianni4,Krum Henry5,Massie Barry6,Zalewski Andrew7,Kandra Albert1,Hua Tsushung A.7,Gimpelewicz Claudio1

Affiliation:

1. Novartis Pharma AG; Basel Switzerland

2. Cardiovascular Division, Department of Medicine; University of Minnesota Medical School; Minneapolis 55455 MN USA

3. Istituto di Ricerche Farmacologiche Mario Negri; Milano Italy

4. Consorzio Mario Negri Sud, Santa Maria Imbaro; Chieti Italy

5. Monash Centre of Cardiovascular Research and Education in Therapeutics, Department of Epidemiology and Preventive Medicine; Alfred Hospital, Monash University; Melbourne Australia

6. University of California, San Francisco and Cardiology Division; San Francisco Veterans Affairs Medical Center; San Francisco USA

7. Novartis Pharmaceuticals Corporation; East Hanover NJ USA

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

Reference31 articles.

1. Clinical epidemiology of heart failure;Mosterd;Heart,2007

2. Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure;Harjola;Eur J Heart Fail,2010

3. 2009 Focused update incorporated into the ACC/AHA2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults;Hunt;J Am Coll Cardiol,2009

4. Early and long-term outcomes of heart failure in elderly persons, 2001-2005;Curtis;Arch Intern Med,2008

5. Renal failure is an independent predictor of mortality in hospitalized heart failure patients and is associated with a worse cardiovascular risk profile;Grigorian;Rev Esp Cardiol,2006

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