Reduced clinical severity during 2022 Shanghai Spring epidemic of SARS-CoV-2 omicron BA.2 variant infection—an integrated account of virus pathogenicity and vaccination effectiveness

Author:

Wu Xingyue1,Chen Yao1,Cao Kangli1,Shen Yao2,Wu Xueling3,Yang Yilin1,Kuang Zhongshu1,Li Qingrun4,Lu Zhenzhen1,Jia Yichen1,Shao Mian1,Gu Guorong1,Wang Xiangwei5,Yao Ye6,Wang Ying7,Chen Shaodie1,Yu Zhigao1,Wei Wei1,Ding Longfei5,Lan Lulu1,Gu Tianwen1,Long Xiangyu1,Sun Jian1,Xing Lingyu1,Shen Jiayuan1,Han Yi1,Luo Yue1,Mu Sucheng1,Lin Mengna16,Zhang Xiaoyan1,Zeng Rong4,Xu Jianqing1,Zhao Guoping89,Huang Lihong16,Song Zhenju16

Affiliation:

1. Department of Emergency Medicine, Clinical Center for Bio-Therapy, Department of Biostatistics, and Department of Urology, Shanghai Key Laboratory of Lung Inflammation and Injury, Zhongshan Hospital, Fudan University , China

2. Department of Respiratory and Critical Care Medicine, Shanghai Pudong Hospital, Fudan University , China

3. Department of Pulmonology, Renji Hospital, Shanghai Jiao Tong University School of Medicine , China

4. Key Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences , China

5. Shanghai Public Health Clinical Center, Fudan University , China

6. Department of Biostatistics, School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, and Shanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University , China

7. Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Institute of Virology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, School of Medicine, Shanghai Jiao Tong University , China

8. State Key Laboratory of Genetic Engineering, Fudan Microbiome Center, School of Life Sciences, Fudan University , China

9. Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences , China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Science and Technology Development Fund

Key R&D Program of Zhejiang Province

Publisher

Oxford University Press (OUP)

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