Validation of Maternal Recall of Iron Folic Supplementation During Antenatal Care in Rural Southern Nepal

Abstract

Abstract Objectives This study's primary objective is to examine the validity of maternal recall of iron folate supplementation during antenatal care and factors associated with accuracy of maternal recall. Methods A longitudinal cohort design was employed for the validation study. The direct observation of all iron folate supplementation (IFA) received during all antenatal care visits at the five study health posts served as the “gold standard” to the maternal report of IFA received collected during a postpartum interview. Individual-level validity was assessed by calculating indicator sensitivity, specificity and area under the receiver operating curve (AUC). The inflation factor (IF) measured population-level bias, comparing the true coverage to the survey measure (maternal report) coverage of IFA. A multivariable log-binomial model was used to assess factors associated with accurate recall. Results The majority (95.8%) of women were observed receiving IFA during pregnancy. Women overreported the number IFA tablets received compared to what was observed during ANC visits. On average the reported number of tablets received was 45 tablets greater than the number observed. Individual-level accuracy of maternal report of any IFA receipt was moderate (AUC = 0.60) and population bias was low (IF = 1.01). However, the individual-level validity was poor across the seven IFA tablet count categories; the AUC for categories ranged from 0.47 to 0.58, indicating a performance that at best was slightly better than a random guess and at worst, misleading. Driven by the trend of maternal overreport, the inflation factor indicated that the survey measure drastically underestimated the prevalence of lower tablet categories and overestimated the prevalence of higher tablet counts. Accuracy of maternal report was not associated with months since last ANC observation nor any maternal characteristics. Conclusions Maternal report of the amount IFA supplementation received during pregnancy produced extremely biased population prevalence and performed comparably to or worse than a random guess for individual level validity. It's imperative to improve this indicator for future use, as it is included in global frameworks, initiatives and national program planning. Funding Sources This research was funded by the Bill and Melinda Gates Foundation.