Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Author:

Kalil Andre C.1,Metersky Mark L.2,Klompas Michael34,Muscedere John5,Sweeney Daniel A.6,Palmer Lucy B.7,Napolitano Lena M.8,O'Grady Naomi P.9,Bartlett John G.10,Carratalà Jordi11,El Solh Ali A.12,Ewig Santiago13,Fey Paul D.14,File Thomas M.15,Restrepo Marcos I.16,Roberts Jason A.1718,Waterer Grant W.19,Cruse Peggy20,Knight Shandra L.20,Brozek Jan L.21

Affiliation:

1. Department  of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha

2. Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington

3. Brigham and Women's Hospital and Harvard Medical School

4. Harvard Pilgrim Health Care Institute, Boston, Massachusetts

5. Department of Medicine, Critical Care Program,  Queens University, Kingston, Ontario, Canada

6. Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego

7. Department of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, State University of New York at Stony Brook

8. Department of Surgery, Division of Trauma, Critical Care and Emergency Surgery, University of Michigan, Ann Arbor

9. Department of Critical Care Medicine, National Institutes of Health, Bethesda

10. Johns Hopkins University School of Medicine, Baltimore, Maryland

11. Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute, Spanish Network for Research in Infectious Diseases, University of Barcelona, Spain

12. Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, Veterans Affairs Western New York Healthcare System, New York

13. Thoraxzentrum Ruhrgebiet, Department of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt Bochum, Germany

14. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha

15. Summa Health System, Akron, Ohio

16. Department of Medicine, Division of Pulmonary and Critical Care Medicine, South Texas Veterans Health Care System and University of Texas Health Science Center at San Antonio

17. Burns, Trauma and Critical Care Research Centre, The University of Queensland

18. Royal Brisbane and Women's Hospital, Queensland

19. School of Medicine and Pharmacology, University of Western Australia, Perth, Australia

20. Library and Knowledge Services, National Jewish Health, Denver, Colorado

21. Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada

Abstract

Abstract It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances. These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), including specialists in infectious diseases, pulmonary diseases, critical care, and surgeons, anesthesiologists, hospitalists, and any clinicians and healthcare providers caring for hospitalized patients with nosocomial pneumonia. The panel's recommendations for the diagnosis and treatment of HAP and VAP are based upon evidence derived from topic-specific systematic literature reviews.

Funder

National Heart, Lung, and Blood Institute

NIH

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Reference6 articles.

1. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia;American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA);Am J Respir Crit Care Med,2005

2. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations;Guyatt;BMJ,2008

3. Information for healthcare professionals: colistimethate (marketed as Coly-Mycin M and generic products);US Food and Drug Administration (FDA)

4. Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients;Garonzik;Antimicrob Agents Chemother,2011

5. Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus;Nation;Lancet Infect Dis,2015

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