Applicability of the surgical risk calculator by the American College of Surgeons in the setting of German patients undergoing complete pancreatectomy: multicentre study using data from the StuDoQ|Pancreas registry

Author:

Höhn Philipp1ORCID,Runde Fabian2,Luu Andreas Minh1ORCID,Fahlbusch Tim1,Fein Daniel1,Klinger Carsten3,Uhl Waldemar1,Belyaev Orlin1,Gutt Carsten,Köninger Jörg,Schnitzbauer Andreas,Schafmayer Clemens,Farkas Stefan,Hartwig Werner,Torge Mees Sören,Klammer Frank,Glanemann Matthias,Ghadimi Michael,Anthuber Matthias,Reißfelder Christoph,Piso Pompiliu,Padberg Winfried,Grützmann Robert,Niedergethmann Marco,Pascher Andreas,Prenzel Klaus,Reith Hans-Bernd,Chromik Ansgar Michael,M Krüger Colin,Bektas Hüseyin,Illert Bertram,Hommann Merten,Ritz Jörg-Peter,Döhrmann Axel,Schäfer Nico,Kraus Thomas,Jäger Mark,Tschmelitsch Jörg,Fleck Ullrich,Pauthner Michael,Tröbs Ute,Stier Albrecht,Krones Carsten,Keck Tobias4,Werner Jens5,Nüssler Natascha6,Bartsch Detlef K7,Germer Christoph-Thomas8,Friess Helmut9,Mönch Christian10,Oldhafer Karl-Jürgen11,Kalff Jörg C12,

Affiliation:

1. Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-Universität Bochum , Bochum , Germany

2. Faculty of Medicine, Ruhr-Universität Bochum , Bochum , Germany

3. StuDoQ Registry, German Society for General and Visceral Surgery , Berlin , Germany

4. Surgical Department, Universitätsklinikum Schleswig-Holstein Campus Lübeck , Lübeck , Germany

5. Department of General, Visceral, Transplant, Vascular and Thoracic Surgery, Klinikum Großhadern, Ludwig-Maximilians-Universität München , München , Germany

6. Department of General and Visceral Surgery, Endocrine Surgery und Coloproctology, Klinikum Neuperlach, Städt. Klinikum München , München , Germany

7. Department of Visceral, Thoracic and Vascular Surgery, Universitätsklinikum Marburg , Marburg , Germany

8. Department of General, Visceral, Vascular and Pediatric Surgery, Universitätsklinik Würzburg , Würzburg , Germany

9. Department of Surgery, Klinikum rechts der Isar, Technische Universität München , München , Germany

10. Department of General, Visceral and Transplant Surgery, Westpfalz-Klinikum Kaiserslautern , Kaiserslautern , Germany

11. Department of Surgery, Asklepios Klinik Barmbek , Barmbek , Germany

12. Department of Visceral, Colorectal Surgery and Proctology, Universitätsklinikum Bonn , Bonn , Germany

Abstract

Abstract Introduction Surgical risk calculators can estimate risk probabilities for postoperative outcomes utilizing patient-specific risk factors. They provide meaningful information for obtaining informed consent. The aim of the present paper was to evaluate the predictive value of the surgical risk calculators by the American College of Surgeons in German patients undergoing total pancreatectomy. Methods Data for patients who underwent total pancreatectomy between 2014 and 2018 were acquired from the Study, Documentation, and Quality Center of the German Society for General and Visceral Surgery. Risk factors were entered manually into the surgical risk calculators and calculated risks were compared with actual outcomes. Results Of the 408 patients analysed, predicted risk was higher in patients with complications except for the prediction of re-admission (P = 0.127), delayed gastric emptying (P = 0.243), and thrombosis (P = 0.256). In contrast, classification of patients into below, above, or average risk by the surgical risk calculators only produced meaningful results for discharge to nursing facility (P < 0.001), renal failure (P = 0.003), pneumonia (P = 0.001), serious complications, and overall morbidity (both P < 0.001). Assessment of discrimination and calibration showed poor results (scaled Brier scores 8.46 per cent or less). Conclusion Overall surgical risk calculator performance was poor. This finding promotes the development of a specific surgical risk calculator applicable to the German healthcare system.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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