Ultra-early initiation of postoperative rehabilitation in the post-anaesthesia care unit after major thoracic surgery: case–control study

Author:

Pastene Bruno12ORCID,Labarriere Ambroise1,Lopez Alexandre1,Charvet Aude1,Culver Aurélien1,Fiocchi David1,Cluzel Armand3,Brioude Geoffrey3,Einav Sharon4,Tankel James5ORCID,Hamidou Zeinab6,D’Journo Xavier Benoit3ORCID,Thomas Pascal3,Leone Marc12,Zieleskiewicz Laurent127,Slim K.,Joris J.,Delaunay L.,Regimbeau J-M.,Ostermann S.,Beyer-Berjot L.,Lavand'homme P.,Lafortune I.,Szymkiewicz O.,Venara A.,Zieleskiewicz L.,Puppo N.,Beaupère S.,

Affiliation:

1. Department of Anaesthesiology and Intensive Care Medicine, Hôpital Nord, Hôpitaux Universitaires de Marseille, Aix Marseille University , Marseille, France

2. Centre for Cardiovascular and Nutrition Research (C2VN), INRA, Aix Marseille Université, INSERM , Marseille, France

3. Department of Thoracic Surgery, Hôpital Nord, Hôpitaux Universitaires de Marseille, Aix Marseille University , Marseille, France

4. Intensive Care Unit of the Shaare Zedek Medical Medical Centre, Hebrew University Faculty of Medicine , Jerusalem, Israel

5. Division of Thoracic Surgery, McGill University Health Centre , Montreal, Quebec, Canada

6. Centre d’Études et de Recherches sur les Services de Santé et Qualité de Vie CEReSS/EA 3279, Hôpitaux Universitaires de Marseille, Aix Marseille University , Marseille, France

7. Department of Digestive and Hepatobiliary Surgery, CHU Estaing , Clermont-Ferrand, France

Abstract

Abstract Background Physiotherapy is a major cornerstone of enhanced rehabilitation after surgery (ERAS) and reduces the development of atelectasis after thoracic surgery. By initiating physiotherapy in the post-anaesthesia care unit (PACU), the aim was to evaluate whether the ultra-early initiation of rehabilitation (in the first hour following tracheal extubation) would improve the outcomes of patients undergoing elective thoracic surgery. Methods A case–control study with a before-and-after design was conducted. From a historical control group, patients were paired at a 3:1 ratio with an intervention group. This group consisted of patients treated with the ultra-early rehabilitation programme after elective thoracic surgery (clear fluids, physiotherapy, and ambulation). The primary outcome was the incidence of postoperative atelectasis and/or pneumonia during the hospital stay. Results After pairing, 675 patients were allocated to the historical control group and 225 patients to the intervention group. A significant decrease in the incidence of postoperative atelectasis and/or pneumonia was found in the latter (11.4 versus 6.7 per cent respectively; P = 0.042) and remained significant on multivariate analysis (OR 0.53, 95 per cent c.i. 0.26 to 0.98; P = 0.045). A subgroup analysis of the intervention group showed that early ambulation during the PACU stay was associated with a further significant decrease in the incidence of postoperative atelectasis and/or pneumonia (2.2 versus 9.5 per cent; P = 0.012). Conclusions Ultra-early rehabilitation in the PACU was associated with a decrease in the incidence of postoperative atelectasis and/or pneumonia after major elective thoracic surgery.

Funder

GRACE Association

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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