1. Research and Development Center, Nitta Gelatin Inc. , Osaka , Japan
2. Department of Neurology and Geriatric Medicine, Ehime University Graduate School of Medicine , Toon City, Ehime , Japan
3. Department of Pathophysiology, Division of Integrative Pathophysiology, Proteo-Science Center, Ehime University Graduate School of Medicine , Toon City, Ehime , Japan
4. Department of Advanced Brain Therapy, Ehime University Graduate School of Medicine , Toon City, Ehime, Japan
5. Department of Anti-Aging Medicine, Ehime University Graduate School of Medicine , Toon City, Ehime , Japan