Executive Summary: A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2013 Recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)a

Author:

Baron Ellen Jo12,Miller J. Michael3,Weinstein Melvin P.4,Richter Sandra S.5,Gilligan Peter H.6,Thomson Richard B.7,Bourbeau Paul8,Carroll Karen C.9,Kehl Sue C.10,Dunne W. Michael1112,Robinson-Dunn Barbara13,Schwartzman Joseph D.14,Chapin Kimberle C.15,Snyder James W.16,Forbes Betty A.17,Patel Robin18,Rosenblatt Jon E.18,Pritt Bobbi S.18

Affiliation:

1. Department of Pathology, Stanford University School of Medicine, Stanford, California

2. Cepheid, R&D, Sunnyvale, California

3. Microbiology Technical Services, LLC, Dunwoody, Georgia

4. Department of Medicine and Pathology, Robert Wood Johnson Medical School, New Brunswick, New Jersey

5. Department of Clinical Pathology, Cleveland Clinic, Cleveland, Ohio

6. Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina

7. Department of Pathology, NorthShore University HealthSystem, Evanston, Illinois

8. Scientific Affairs, BD Diagnostics, Sparks, Maryland

9. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland

10. Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin

11. bioMerieux, Inc, Durham, North Carolina

12. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri

13. Department of Pathology, William Beaumont Hospital to Beaumont Health System, Royal Oak, Michigan

14. Department of Pathology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire

15. Department of Pathology, Brown Alpert Medical School, Providence, Rhode Island

16. Department of Laboratory Medicine, University of Louisville, Kentucky

17. Department of Pathology, Virginia Commonwealth University Medical Center, Richmond, Virginia

18. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota

Abstract

Abstract The critical role of the microbiology laboratory in infectious disease diagnosis calls for a close, positive working relationship between the physician and the microbiologists who provide enormous value to the health care team. This document, developed by both laboratory and clinical experts, provides information on which tests are valuable and in which contexts, and on tests that add little or no value for diagnostic decisions. Sections are divided into anatomic systems, including Bloodstream Infections and Infections of the Cardiovascular System, Central Nervous System Infections, Ocular Infections, Soft Tissue Infections of the Head and Neck, Upper Respiratory Infections, Lower Respiratory Tract infections, Infections of the Gastrointestinal Tract, Intraabdominal Infections, Bone and Joint Infections, Urinary Tract Infections, Genital Infections, and Skin and Soft Tissue Infections; or into etiologic agent groups, including Tickborne Infections, Viral Syndromes, and Blood and Tissue Parasite Infections. Each section contains introductory concepts, a summary of key points, and detailed tables that list suspected agents; the most reliable tests to order; the samples (and volumes) to collect in order of preference; specimen transport devices, procedures, times, and temperatures; and detailed notes on specific issues regarding the test methods, such as when tests are likely to require a specialized laboratory or have prolonged turnaround times. There is redundancy among the tables and sections, as many agents and assay choices overlap. The document is intended to serve as a reference to guide physicians in choosing tests that will aid them to diagnose infectious diseases in their patients.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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