Restoring p53 in cancer: the promises and the challenges
Author:
Affiliation:
1. Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Funder
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Cell Biology,Genetics,Molecular Biology,General Medicine
Link
http://academic.oup.com/jmcb/advance-article-pdf/doi/10.1093/jmcb/mjz063/29193365/mjz063.pdf
Reference30 articles.
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3. Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy;Bossi;Cell Cycle,2008
4. When mutants gain new powers: news from the mutant p53 field;Brosh;Nat. Rev. Cancer,2009
5. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis;Chen;Nature,2005
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