BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells-Reference-Cited by-同舟云学术

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BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells

Published:2020-01-03 Issue:5 Volume:12 Page:397-399
ISSN:1759-4685
Container-title:Journal of Molecular Cell Biology
language:en
Short-container-title:

Author:

Antony Jisha¹²,Gimenez Gregory¹,Taylor Terry³,Khatoon Umaima¹,Day Robert⁴,Morison Ian M¹,Horsfield Julia A¹²

Affiliation:

1. Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin 9016, New Zealand

2. Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland, New Zealand

3. Southern Community Laboratories, Dunedin 9016, New Zealand

4. Department of Biochemistry, University of Otago, Dunedin 9054, New Zealand

Funder

Health Research Council of New Zealand

Cancer Research Trust New Zealand

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/jmcb/advance-article-pdf/doi/10.1093/jmcb/mjz114/33129261/mjz114.pdf

Reference10 articles.

1. Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1;Benedetti;Oncotarget,2017

2. BET bromodomain inhibition releases the mediator complex from select cis-regulatory elements;Bhagwat;Cell Rep.,2016

3. Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization;Kojic;Nat. Struct. Mol. Biol.,2018

4. Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms;Kon;Nat. Genet.,2013

5. In situ capture of chromatin interactions by biotinylated dCas9;Liu;Cell,2017

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3. Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML;Science Translational Medicine;2024-01-03

4. Down syndrome and leukemia: An insight into the disease biology and current treatment options;Blood Reviews;2023-11

5. Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS/AML;2022-09-27

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