Affiliation:
1. Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20850, USA
2. Radio & Satellite Research Division, Electronics and Telecommunications Research Institute, Daejeo 34129, South Korea
Abstract
Abstract
Over the past decades, the application of single-photon emission computed tomography and positron emission tomography in neuroimaging has markedly increased. In the current study, we used a series of Korean computational head phantoms with detailed cranial structures for 6-, 9-, 12-, 15-y-old children and adult and a Monte Carlo transport code, MCNPX, to calculate age-dependent specific absorbed fraction (SAF) for mono-energetic electrons ranging from 0.01 to 4 MeV and S values for seven radionuclides widely used in nuclear medicine neuroimaging for the combination of ten source and target regions. Compared to the adult phantom, the 6-y phantom showed up to 1.7-fold greater SAF (cerebellum < cerebellum) and up to 1.4-fold greater S values (vitreous body < lens) for 123I. The electron SAF data, combined with our previous photon SAF data, will facilitate absorbed dose calculations for various cranial structures in patients undergoing neuroimaging procedures.
Funder
Ministry of Science, ICT and Future Planning
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Public Health, Environmental and Occupational Health,Radiology Nuclear Medicine and imaging,General Medicine,Radiation,Radiological and Ultrasound Technology
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